779355-69-0Relevant academic research and scientific papers
Bis(pyrazolyl)methane Copper Complexes as Robust and Efficient Catalysts for Sonogashira Couplings
Moegling, Julian,Benischke, Andreas D.,Hammann, Jeffrey M.,Vepek, Nynke A.,Zoller, Florian,Rendenbach, Bettina,Hoffmann, Alexander,Sievers, Holger,Schuster, Michael,Knochel, Paul,Herres-Pawlis, Sonja
, p. 7475 - 7483 (2016/01/25)
A series of bis(pyrazolyl)methane copper complexes were found to catalyze a fast palladium-free Sonogashira coupling reaction of several iodoarenes with terminal alkynes such as phenylacetylene, propargyl benzyl ether, and (tert-butyl-dimethyl)silylacetyl
Facile synthesis of substituted alkynes by nano-palladium catalyzed oxidative cross-coupling reaction of arylboronic acids with terminal alkynes
Nie, Xiaopeng,Liu, Suli,Zong, Yan,Sun, Peipei,Bao, Jianchun
experimental part, p. 1570 - 1573 (2011/06/17)
The oxidative cross-coupling of terminal alkynes with arylboronic acids catalyzed by the porous palladium nanospheres was developed. In the presence of silver oxide, triphenylphosphine and cesium carbonate, the reaction provided the corresponding arylalkynes with good to excellent yields. There were also other obvious advantages such as broad applicability, high selectivity, simple experimental operation as well as the convenient preparation, high efficiency and reusability of catalyst. The possible mechanism of this transition-metal nanoparticles catalyzed oxidative cross-coupling reaction of two nucleophiles was proposed.
Gold(I)-catalyzed rearrangement of propargyl benzyl ethers: A practical method for the generation and in situ transformation of substituted allenes
Bolte, Benoit,Odabachian, Yann,Gagosz, Fabien
supporting information; experimental part, p. 7294 - 7296 (2010/08/05)
A series of benzyl propargyl ethers react with a gold(I) catalyst to furnish variously substituted allenes via a 1,5-hydride shift/fragmentation sequence. This transformation is rapid and practical. It can be performed under very mild conditions (room temperature or 60 °C) using terminal as well as substituted alkyne substrates bearing a primary, secondary, or tertiary benzyl ether group. The allenes thus formed can be reacted in situ with an internal or external nucleophile, corresponding to an overall reductive substitution process, to produce more functionalized compounds.
