77940-94-4

Basic information

• Product Name: 3-PIPERIDINOBENZOIC ACID
• Synonyms: 3-PIPERIDINOBENZOIC ACID;3-PIPERIDIN-1-YL-BENZOIC ACID;ASINEX-REAG BAS 12456716;TIMTEC-BB SBB010196;1-(3-Carboxyphenyl)piperidine;3-(1-Piperidinyl)benzoic acid
• CAS NO: 77940-94-4
• Molecular Formula: C₁₂H₁₅NO₂
• Molecular Weight: 205.25
• Mol File: 77940-94-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 120 °C
• Boiling Point: 395.5°C at 760 mmHg
• Flash Point: 193°C
• Appearance: /
• Density: 1.178g/cm³
• Vapor Pressure: 5.76E-07mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 3-PIPERIDINOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PIPERIDINOBENZOIC ACID(77940-94-4)
• EPA Substance Registry System: 3-PIPERIDINOBENZOIC ACID(77940-94-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 77940-94-4(Hazardous Substances Data)

Usage

General Description

3-piperidinobenzoic acid is a chemical compound belonging to the group of benzoic acids. It consists of a piperidine ring and a benzoic acid functional group. It is used in the synthesis of pharmaceuticals and acts as a building block for various biologically active molecules. 3-PIPERIDINOBENZOIC ACID has been studied for its potential anticonvulsant and anti-inflammatory properties. Additionally, 3-piperidinobenzoic acid is used as an intermediate in the production of various drugs and organic compounds. Its unique structure and versatility make it an important chemical in the field of medicinal chemistry and drug development.

InChI:InChI=1/C12H15NO2/c14-12(15)10-5-4-6-11(9-10)13-7-2-1-3-8-13/h4-6,9H,1-3,7-8H2,(H,14,15)

Upstream product

• 57489-59-5 3-piperidin-1-yl-benzoic acid methyl ester 
• 168162-26-3 methyl 3-(4-pentenoylamino)benzoate 
• 111-24-0 1,5-dibromo-pentane 
• 99-05-8 meta-aminobenzoic acid 
• 168162-27-4 methyl 3-(5-bromopentanoylamino)benzoate 
• 168162-37-6 3-(5-Hydroxy-pentanoylamino)-benzoic acid methyl ester 
• 591-80-0 pent-4-enoic acid 
• 168162-28-5 methyl 3-(2-oxopiperidin-1-yl)benzoate 
• 39716-58-0 pent-4-enoyl chloride 
• 4518-10-9 Methyl 3-aminobenzoate 

Relevant articles and documents

QUINAZOLINONE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS

The invention relates to chemical compounds of the formula (I): or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.

Process of preparing benzodiazepine compounds useful as antagonists of CCK or of gastrine

A benzodiazepine derivative of formula I, or a pharmaceutically acceptable salt thereof: STR1 wherein: (a) R4 is an alkyl, cycloalkyl or aryl group. (b) R10 is chosen from halo, OH, CH3, OCH3, NR11 R12, NO2, NHCHO, CO2 H and CN, and R11 and R12 are independently selected from H and alkyl (C1 -C5) or together NR11 R12 form a cyclic structure II, STR2 wherein a is 1-6; and (c) R2 is an aromatic 5- or 6-membered, substituted or unsubstituted heterocycle containing at least two heteroatoms of which at least one is nitrogen. These compounds are gastrin and/or CCK-B receptor antagonists.