77972-82-8 Usage
Uses
Used in Organic Synthesis:
CYCLOPROPYL 3-FLUOROPHENYL KETONE is utilized as a building block in organic synthesis for the preparation of a wide range of pharmaceuticals and agrochemicals. Its unique structural features contribute to the development of novel and effective compounds in these industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, CYCLOPROPYL 3-FLUOROPHENYL KETONE is used as a key intermediate in the synthesis of various drug molecules. Its cyclopropyl and fluorophenyl groups can enhance the pharmacological properties of the resulting compounds, such as potency, selectivity, and metabolic stability.
Used in Agrochemical Industry:
CYCLOPROPYL 3-FLUOROPHENYL KETONE also finds application in the agrochemical industry, where it serves as a precursor for the synthesis of pesticides and other crop protection agents. CYCLOPROPYL 3-FLUOROPHENYL KETONE's unique characteristics can lead to the development of more effective and environmentally friendly agrochemicals.
Used in Transition Metal Catalysis:
CYCLOPROPYL 3-FLUOROPHENYL KETONE has been studied for its potential use as a ligand in transition metal catalysis. Its presence can improve the efficiency and selectivity of catalytic reactions, which is crucial for the synthesis of complex organic molecules and the development of greener chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 77972-82-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,9,7 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 77972-82:
(7*7)+(6*7)+(5*9)+(4*7)+(3*2)+(2*8)+(1*2)=188
188 % 10 = 8
So 77972-82-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H9FO/c11-9-3-1-2-8(6-9)10(12)7-4-5-7/h1-3,6-7H,4-5H2
77972-82-8Relevant academic research and scientific papers
A cascade approach to fused indolizinones through Lewis acid-copper(i) relay catalysis
Huang, Huawen,Ji, Xiaochen,Wu, Wanqing,Jiang, Huanfeng
supporting information, p. 3351 - 3353 (2013/06/04)
A relay catalytic cascade process involving Lewis acid triggered ring-opening of cyclopropyl ketones with nitriles, the copper(i)-catalyzed Ritter process, and acid-promoted N-acyliminium ion cyclization is described, which efficiently provides thieno-, furano-, and benzo-indolizinones in moderate to good yields. The Royal Society of Chemistry 2013.
Synthesis of Some Substituted Pyrrolidines from Cyclopropyl Carbonyl Compounds
Blake, Keith W.,Gillies, Iain,Denney, Ronald C.
, p. 700 - 702 (2007/10/02)
A series of alkyl and aryl cyclopropyl carbonyl compounds, when refluxed in N-methylformamide in the presence of magnesium chloride, gave variously substituted pyrrolidines.
