77976-34-2

Usage

Heterocyclic compound

Triazolopyrimidine ring structure

Functional group

Thione

Biological activity

Anticonvulsant and anxiolytic properties

Potential applications

Pharmaceutical research and drug development

Interesting target

Unique chemical structure and properties

Upstream product

• 75-15-0 carbon disulfide 
• 28539-30-2 4-amino-5-aminomethyl-1-methyl-1,2,3-triazole 

Relevant academic research and scientific papers

v-Triazolopyrimidines (8-Azapurines). Part 23. Synthesis and Properties of N-Alkyl-1,6-dihydro-8-azapurin-2-thiones. Migration (N->N') of Acyl Group in 5-Aminomethyl-4-oxamoylamino-1,2,3-triazoles

1,6-Dihydro-7-(and 8-)methyl-8-azapurine-2-thione (1a and b) were made by the action of carbon disulphide on 4-amino-5-aminomethyl-1-(and 2)-methyl-1(and 2)H-1,2,3-triazole (2c and b) respectively.These thiones were methylated to the corresponding 2-methy

Derivatives of 3H-1,2,3-Triazolothiazine, a New Heterocyclic Nucleus. Some Shifts of a Methylene Group from a Nitrogen to a Sulphur Atom

Contrary to expectations, 3-alkyl derivatives of 4-amino-5-aminomethyl-3H-1,2,3-triazole (2b and 2c), when heated with carbon disulphide and a base, did not give a 1,3,6,9-tetrahydro-8-azapurine-2-thione (3b) but a 3-alkyl-3,7-dihydro-1,2,3-triazolo4,5-d