77996-13-5

Basic information

• Product Name: 2(1H)-Naphthalenone, 3,4-dihydro-1-hydroxy-7-methoxy-1,6-dimethyl-4-(1-methylethyl)-
• CAS NO: 77996-13-5
• Molecular Formula: C16H22O3
• Mol File: 77996-13-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2(1H)-Naphthalenone, 3,4-dihydro-1-hydroxy-7-methoxy-1,6-dimethyl-4-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Naphthalenone, 3,4-dihydro-1-hydroxy-7-methoxy-1,6-dimethyl-4-(1-methylethyl)-(77996-13-5)
• EPA Substance Registry System: 2(1H)-Naphthalenone, 3,4-dihydro-1-hydroxy-7-methoxy-1,6-dimethyl-4-(1-methylethyl)-(77996-13-5)

Safety Data

• Hazardous Substances Data: 77996-13-5(Hazardous Substances Data)

Upstream product

• 77996-14-6 (4-Isopropyl-7-methoxy-1,6-dimethyl-3,4-dihydro-naphthalen-2-yloxy)-trimethyl-silane 
• 80713-20-8 methyl β-(3-methyl-4-methoxybenzoyl)propionate 
• 77996-10-2 4-Hydroxy-4-(4-methoxy-3-methylphenyl)-5-methyl-hexanoic Acid Lactone 
• 77996-11-3 4-Isopropyl-7-methoxy-1,6-dimethyl-1,2,3,4-tetrahydro-naphthalen-1-ol 
• 2954-68-9 4-(4-methoxy-3-methylphenyl)-4-oxo-butyric acid ethyl ester 
• 80736-45-4 1,2,3,4-Tetrahydro-4-isopropyl-7-methoxy-6-methyl-1-naphthalenone 
• 70143-25-8 7-Methoxy-α-calacorene 
• 70143-24-7 4-(4-methoxy-3-methylphenyl)-5-methylhexanoic acid 
• 68233-93-2 1,2,3,4-Tetrahydro-4-isopropyl-7-methoxy-1,6-dimethyl-2-naphthalenone 
• 208040-52-2 7‐methoxy‐1,6‐dimethylnaphthalen‐2‐ol 
• 33446-15-0 4-(4-methoxy-3-methylphenyl)butyric acid 
• 107203-19-0 7-Methoxy-1.6-dimethyl-tetralon-⁽²⁾ 
• 107203-36-1 6-methoxy-4,7-dimethyl-1,2-dihydronaphthalene 
• 33446-14-9 4-(4-methoxy-3-methylphenyl)-4-oxobutyric acid 

Downstream Products

• 87900-51-4 lacinilene C 
• 56051-00-4 1-hydroxy-4-isopropyl-7-methoxy-1,6-dimethylnaphthalen-2(1H)-one 

Relevant articles and documents

Isolation and synthesis of two antiproliferative calamenene-type sesquiterpenoids from Sterculia tavia from the Madagascar Rain Forest

Investigation of the endemic Madagascan plant Sterculia taiva Baill. (Malvaceae) for antiproliferative activity against the A2780 ovarian cancer cell line led to the isolation of two new bioactive calamenene-type sesquiterpenoids, named tavinin A (2) and

Gossypium Cadinanes and Their Analogues: Synthesis of Lacinilene C, 2,7-Dihydroxycadalene, and Their Methyl Ethers

The total synthesis of lacinilene C methyl ether has been accomplished in ten steps with an overall, optimal yield of 38percent by starting with o-methylanisole.Formation of the key α-aryl-α-ketol functionality, which is particularly sensitive to oxidation, was accomplished by stepwise oxidation reactions based on the use of N-methylmorpholine N-oxide/osmium tetraoxide acting on alkene and trimethylsilyl enol ether functionality.Other oxidations could be accomplished by using dichlorodicyanobenzoquinone to generate unsaturation adjacent to the α-ketol group or to form substituted naphtalenes.These reactions permitted adjustment of the oxidation level and oxygenation pattern of the key intermediate, 7-methoxy-α-calacorene (3,4-dihydro-4-isopropyl-7-methoxy-1,6-dimethylnaphthalene), to accomplish the synthesis of 2-hydroxy-7-methoxycadalene, 2,7-dihydroxycadalene, 7-methoxycadalene, and 7-hydroxycadalene, in addition to lacinilene C and its methyl ether.