78009-15-1Relevant academic research and scientific papers
Synthesis of mono- and diaza-'pyridones' via stille coupling of alkoxystannanes
Smith, Charlotte L.,Hirschh?user, Christoph,Malcolm, Georgia K.,Nasrallah, Daniel J.,Gallagher, Timothy
, p. 1904 - 1908 (2014/08/18)
Various alkoxy-substituted heterocyclic stannanes provide access to the corresponding substituted 'pyridone' moieties via Stille cross-coupling. Both pyridyl and a series of diazinyl stannanes are prepared, and options for unmasking (via demethylation or debenzylation) of the pyridone unit are evaluated. Georg Thieme Verlag Stuttgart. New York.
A method for the reductive scission of heterocyclic thioethers
Graham, Thomas H.,Liu, Wensheng,Shen, Dong-Ming
supporting information; experimental part, p. 6232 - 6235 (2012/01/03)
A mild, chemoselective, and generally high-yielding method for the reductive scission of heterocyclic thioethers is described. Suitable heterocycles have a thioether substituent at the 2-position relative to a ring heteroatom. The convenient and straightforward method is demonstrated with reactants which are not compatible with the standard Raney nickel conditions such as sulfides, sulfones, and thiophenes. In addition, benzyl esters, benzyl amides, and benzyl carbamates are tolerated by the reductive reaction conditions.
Reaction of Substituted 4-Phenylpyrimidine 1,3-Dioxides with Phosphorus Oxychloride
Tikhonov, A. Ya.,Sedova, V. F.,Volodarskii, L. B.,Mamaev, V. P.
, p. 383 - 386 (2007/10/02)
2-Chloropyrimidine 1-oxides are formed in the reaction of substituted 4-phenylpyrimidine 1,3-dioxides with phosphorus oxychloride; in addtition, 2,4-dichloropyrimidines and 3-phenylisoxazoles were isolated.
