78012-18-7Relevant academic research and scientific papers
Structure and Synthesis of Pallescensin E Utilising a Modified Wadsworth-Emmons Reaction
Baker, Raymond,Sims, Russell
, p. 3087 - 3091 (2007/10/02)
A modified Wadsworth-Emmons reaction using a catalytic amount of 15-crown-5 has been employed in the synthesis of the naturally occurring furosesquiterpene pallescensin E.The structure of this compound has been confirmed by comparison of its spectral data with those of the synthesised isomer, 9,10-dihydro-7,8-dimethyl-4H-benzocycloheptafuran.
SYNTHESIS OF PALLESCENSIN-E : USE OF CROWN ETHER IN THE WADSWORTH PROCEDURE FOR OLEFIN FORMATION
Baker, R.,Sims, R. J.
, p. 161 - 162 (2007/10/02)
The furanosesquiterpene, pallescensin-E has been prepared by a route involving reaction of a dimethyl 3-furylmethyl phosphonate anion with 2,3-dimethylbenzaldehyde in the presence of 15-crown-5; this reaction has been shown to have general applicability.
