78016-80-5Relevant academic research and scientific papers
Michael-additions of 6-aminopyrimidin-4-ones to enones: Semi-empirical MO calculations and experimental investigations
Troschutz,Anders
, p. 341 - 348 (2007/10/02)
AM1- and PM3 calculations reveal a satisfactory correlation between the charge densities at the C-5 atom (q(C-5), Table 2) of compounds 1, 2, 4a-c and their enamine-like nucleophilicity towards enones 3 and 9. Furthermore, in this series the similarity of
Synthesis of Heterocycles : Part IV - Pyridopyrimidines
Rao, A. Subba,Mitra, R. B.
, p. 159 - 160 (2007/10/02)
5,7-Disubstituted pyridopyrimidine-2,4-diones (Va-c) have been synthesized by a new route involving Michael addition of 1,3-dimethyl-6-iminouracil (I) to α-enones (IIa-c).Reaction of I and benzalacetone (IId) furnishes 9H-pyrimido-quinoline derivatives (VI, VII).
