78037-98-6

Upstream product

• 67-56-1 methanol 
• 742103-77-1 6-((3Z,6Z,9Z)-1-iodopentadeca-3,6,9-trien-1-yl)tetrahydro-2Hpyran-2-one 
• 65090-68-8 dodeca-3,6-diyn-1-ol 
• 85924-34-1 Methanesulfonic acid (3Z,6Z)-dodeca-3,6-dienyl ester 
• 111689-72-6 (R)-5-Benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pentanoic acid ethyl ester 
• 81345-05-3 (Z,Z)-1-iodo-3,6-dodecadiene 
• 83685-97-6 (R)-5-Benzyloxy-6-oxo-hexanoic acid ethyl ester 
• 86535-43-5 ((3Z,6Z)-Dodeca-3,6-dienyl)-triphenyl-phosphonium; chloride 
• 29125-78-8 (Z,Z)-3,6-dodecadien-1-ol 
• 81517-87-5 6-((1E,3Z,6Z,9Z)-pentadeca-1,3,6,9-tetraen-1-yl)tetrahydro-2Hpyran-2-one 

Relevant academic research and scientific papers

A PRACTICAL PROCESS FOR LARGE-SCALE SYNTHESIS OF (S)-5-HYDROXY-6-TRANS-8,11,14-CIS-EICOSATETRAENOIC ACID (5-HETE)

(S)-5-hydroxy-6-trans-8,11,14-cis-eicosatetraenoic acid (5-HETE) (1) and its enantiomer are readily available by a chemical synthesis from arachidonic acid which includes a chromatographic separation of diastereomeric urethanes (3) made from (+/-)-5-HETE methyl ester and the isocyanate 4 derived from dehydroabietylamine.