78076-53-6

Upstream product

• 78076-52-5 1,2-dihydro-1-(4'-methylphenyl)naphtho<2,1-b>thiophene 
• 233-02-3 naphtho[2,1-b]thiophene 
• 108-88-3 toluene 
• 941-98-0 1'-naphthacetophenone 
• 5720-05-8 4-methylphenylboronic acid 
• 102421-44-3 4-methyl-N'-(1-(naphthalen-1-yl)ethylidene)benzenesulfonohydrazide 

Relevant academic research and scientific papers

One-pot reductive coupling reactions of acetyl naphthalene derivatives, tosylhydrazide, with arylboronic acids

In this study, a one-pot two-step reductive coupling between acetyl naphthalene derivatives, tosylhydrazide, and arylboronic acids, affording substituted 1(or 2)-(1-phenylethyl)naphthalenes in moderate-to-excellent yields, was reported. Notably, solvent played a crucial role in the coupling of 1-acetyl naphthalene derivatives (toluene) or 2-acetyl naphthalene derivatives (1,4-dioxane) as starting materials. Meanwhile, the scope of this one-pot coupling reaction was extended to 1(or 2)-naphthaldehyde substrates. Particularly, the system was also suitable to synthesize 1(or 2)-(1-phenylethyl)naphthalenes on a multi-gram scale, and was applied in the synthesis of naphthylmethyl substituted carbazolyl compounds.

THE ADDITION OF SIMPLE AROMATIC HYDROCARBONS TO CONDENSED AROMATIC THIOpheNES PROMOTED BY ALUMINUM CHLORIDE. PART I. NAPHTHOTHIOPHENE

Naphthothiophenes are the major products and at higher temperatures 2-arylnaphthothiophenes rwesult. 1-Arylnaphthothiophenes may be prepard by treatment of the dihydro-addition products with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone thus giving a new synthesis of 1- 2-arylnaphthothiophenes from the parent heterocycle.