780791-08-4Relevant academic research and scientific papers
AuIII-Catalyzed Formation of α-Halomethyl Ketones from Terminal Alkynes
Xing, Yalan,Zhang, Ming,Ciccarelli, Sarah,Lee, John,Catano, Bryant
, p. 781 - 785 (2017/02/15)
A AuIII-catalyzed synthesis of α-halomethyl ketones from terminal alkynes was developed. This approach features excellent functional group compatibility and good yields for both aromatic and aliphatic terminal alkynes. The resulting α-halomethyl ketones were used to prepare heterocyclic indolizine structures. The plausible mechanism of the one-pot reaction is proposed.
Iodine-promoted synthesis of acylindolizine derivatives from acetylenecarboxylates and pyridinium, isoquinolinium, or quinolinium ylides
Liu, Juanjuan,Yan, Peiyun,Li, Yan,Zhou, Zhengquan,Ye, Weijian,Yao, Juan,Wang, Cunde
, p. 617 - 625 (2014/04/03)
An iodine-promoted synthesis of acylindolizinecarboxylates via 1,3-dipolar cycloaddition of nitrogen ylides with acetylenecarboxylates and subsequent aromatization for the generation of a wide range of structurally interesting, pharmacologically and photoelectrically significant compounds is reported. Only readily available materials, mild conditions, and operationally trivial reaction protocols were required. Graphical abstract: [Figure not available: see fulltext.]
Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: Antibacterial and antifungal evaluation of the products
Hazra, Abhijit,Mondal, Shyamal,Maity, Arindam,Naskar, Subhendu,Saha, Pritam,Paira, Rupankar,Sahu, Krishnendu B.,Paira, Priyankar,Ghosh, Soma,Sinha, Chandrima,Samanta, Amalesh,Banerjee, Sukdeb,Mondal, Nirup B.
, p. 2132 - 2140 (2011/06/21)
A number of indolizines and pyrrolo[1,2-a]quinolines/isoquinolines were prepared from phenacyl pyridinium, quinolinium and isoquinolinium salts derived fromthe reaction of the heterocycles with 2-bromo acetophenone with alkynes and alkenes using amberlite-IRA-402 (OH) ion exchange resin as the base. Antibacterial and antifungal studies were carried out against thirteen bacterial and four fungal strains, which revealed that three derivatives (4a, 4b, 7a) out of fifteen are effective against all the thirteen strains and one derivative, 10, showed dual antibactericidal and antifungal efficacy.
