78095-32-6 Usage
Description
(R)-8-methoxy-N-propyl-2-aminotetraline hydrochloride, a chemical compound belonging to the class of amines, is the hydrochloride salt form of (R)-8-methoxy-N-propyl-2-aminotetraline. It functions as a selective dopamine D2-like receptor agonist, which has been investigated for its potential therapeutic applications in various psychiatric, neurological, and substance abuse disorders. Its pharmacological and neuroprotective effects have garnered significant interest in the medical field.
Uses
Used in Pharmaceutical Industry:
(R)-8-methoxy-N-propyl-2-aminotetraline hydrochloride is used as a therapeutic agent for its potential in treating psychiatric and neurological disorders. Its agonistic action on dopamine D2-like receptors makes it a promising candidate for conditions such as schizophrenia, Parkinson's disease, and other related disorders.
Used in Neuroprotection:
In the field of neuroprotection, (R)-8-methoxy-N-propyl-2-aminotetraline hydrochloride is utilized for its potential to protect neurons from damage and degeneration, which could be beneficial in the treatment of neurodegenerative diseases like Alzheimer's and Huntington's disease.
Used in Substance Abuse Treatment:
(R)-8-methoxy-N-propyl-2-aminotetraline hydrochloride is also used as a potential treatment for substance abuse and addiction. Its interaction with dopamine receptors may help in managing withdrawal symptoms and reducing cravings, thus aiding in the recovery process.
Used in Research and Development:
This chemical compound is used as a research tool in the development of new drugs and therapies targeting dopamine D2-like receptors. Its study contributes to a deeper understanding of the receptor's role in various physiological and pathological processes, which can lead to the creation of more effective treatments for a range of conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 78095-32-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,0,9 and 5 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 78095-32:
(7*7)+(6*8)+(5*0)+(4*9)+(3*5)+(2*3)+(1*2)=156
156 % 10 = 6
So 78095-32-6 is a valid CAS Registry Number.
78095-32-6Relevant articles and documents
8-Hydroxy-2-(alkylamino)tetralins and related compounds as central 5-hydroxytryptamine receptor agonists
Arvidsson,Hacksell,Johansson,Nilsson,Lindberg,Sanchez,Wikstroem,Svensson,Hjorth,Carlsson
, p. 45 - 51 (2007/10/02)
A series of 2-(alkylamino)tetralins related to 8-hydroxy-2-(di-n-propylamino)tetralin (21) were prepared and tested as dopamine (DA) and 5-hydroxytryptamine (5-HT) receptor agonists. Several of the compounds were potent 5-HT agonists devoid of DA-mimetic effects. N-Ethyl or N-propyl substitution of 8-hydroxy-2-aminotetralin gave the most potent agonists. It was shown that the most potent compound, (+)-21, has the 2R configuration. 5,8-Dimethoxy-2-(di-n-propylamino)tetralin (31) was found to be a weak DA agonist devoid of 5-HT activity. The corresponding indan derivative, 4,7-dimethoxy-2-(di-n-propylamino)indan (39), has been reported to be active on both DA and 5-HT receptors. The 5-HT-stimulating properties of compounds 21 and 39 as compared to the incapability of compound 31 to activate the 5-HT receptor is tentatively explained by the assumed mode of binding of the compounds to the 5-HT receptor.
