78109-50-9Relevant academic research and scientific papers
Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-ones
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, (2008/06/13)
Process for 4-halo azetidinones of the formula STR1 wherein R1 is acylamino or diacylamino, X is chloro, bromo or iodo, and R is a carboxy-protecting group which comprises treating a 4-sulfinoazetidinone of the formula STR2 with positive haloge
Azetidinone Antibiotics. 22. A Rearrangement of Oxoazetidinesulfinic Acids to Haloazetidinones
Spitzer, Wayne A.,Goodson, Theodore,Lammert, Steven R.,Kukolja, Stjepan
, p. 3568 - 3570 (2007/10/02)
Treatment of the oxoazetidinesulfinic acid 3 with a positive halogen source gave trans and cis 4-haloazetidinones 5; the trans isomer of 5 are easily converted to oxazoline 6 by chromatography on silica gel, while the cis isomers are transformed into 6 by
