78138-03-1

Upstream product

• 100-39-0 benzyl bromide 
• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 
• 65-71-4 2,4-dihydroxy-5-methylpyrimidine 
• 6160-49-2 1-O-acetyl-3,5-di-O-benzyl-2-deoxy-D-erythro-pentofuranose 
• 132487-16-2 methyl 3,5-di-O-benzyl-2-deoxy-D-ribofuranoside 
• 6160-50-5 3,5-di-O-benzyl-2-deoxy-D-ribofuranose 
• 270918-00-8 (2R,3S)-3-Benzyloxy-2-benzyloxymethyl-5-chloro-tetrahydro-furan 
• 7288-28-0 2,4-bis(trimethylsiloxy)-5-methylpyrimidine 
• 133658-23-8 (2R,3S)-3-(benzyloxy)-2-(benzyloxymethyl)-5-(phenylthio)tetrahydrofuran 

Downstream Products

• 137121-87-0 α/β-D-thymidine 

Relevant academic research and scientific papers

Efficient electrochemical N-glycosylation of silylated pyrimidines with protected arylthioriboses in the presence of a catalytic amount of NBS or Br2

Electrolysis of silylated pyrimidines with protected arylthioribose, in the presence of a catalytic amount of NBS or Br2 as a mediator in an undivided cell, gave the corresponding N-glycosides (nucleosides) in good yield.

Stereoselective Synthesis of β-2-Deoxyribonucleosides from 1-O-Acetyl-3-O--2-deoxyribose

β-2-Deoxyribonucleosides are prepared stereoselectively from 1-O-acetyl-5-O-benzyl-3-O--2-deoxy-D-erythro-pentofuranose by the reaction with the silyl or zinc derivatives of nucleoside bases in the presence of trimethylsilyl trifl

STEREOCHEMICAL CONTROL AS A FUNCTION OF PROTECTING-GROUP PARTICIPATION IN 2-DEOXY-D-ERYTHRO-PENTOFURANOSYL NUCLEOSIDES

Possible features controlling the anomeric ratios in the synthesis of the antiviral antibiotic dihydro-5-azathymidine have been examined.Replacement of the 3- and 5-(4-methylbenzoyl) protecting groups in 2-deoxy-D-erythro-pentofuranosyl chloride by benzyl