781642-75-9

Upstream product

• 70-23-5 ethyl Bromopyruvate 
• 781642-73-7 2,5-anhydro-3-azido-6-O-benzoyl-3-deoxy-D-allonothioamide 
• 781642-72-6 2,5-anhydro-3-azido-6-O-benzoyl-4-O-benzyl-3-deoxy-D-allonothioamide 
• 781642-71-5 2,5-anhydro-3-azido-6-O-benzoyl-4-O-benzyl-3-deoxy-D-allononitrile 
• 228399-09-5 2,5-anhydro-3-azido-6-O-benzoyl-4-O-benzyl-3-deoxy-D-allose ethylene acetal 

Relevant academic research and scientific papers

Synthesis and in vitro antitumour activity of tiazofurin analogues with nitrogen functionalities at the C-2′ position

Synthesis of three tiazofurin (1) isosteres with nitrogen functionalities at the C-2′ position (N3, NH2 and NH3+Cl-) has been achieved, in multistep sequences, starting from monoacetone d-glucose. A n

Synthesis and biological evaluation of two novel 2′-substituted tiazofurin analogues

Two novel tiazofurin analogues, 2-(2-benzamido-2-deoxy-β-d- ribofuranosyl)thiazole-4-carboxamide 4 and 2-(2-azido-2-deoxy-β-d- ribofuranosyl)thiazole-4-carboxamide 5, have been synthesized starting from d-glucose and evaluated for their in vitro cytotoxicity against several human leukaemia and solid tumour cell lines.