781675-82-9

Upstream product

• 42471-59-0 1-bromo-3-(methoxymethoxy)benzene 
• 142570-56-7 [2-(methoxy-methyl-carbamoyl)-ethyl]-carbamic acid tert-butyl ester 
• 1141782-60-6 tert-butyl 3-(3-hydroxyphenyl)-3-oxopropylcarbamate 
• 107-30-2 chloromethyl methyl ether 
• 1141782-09-3 tert-butyl 3-hydroxy-3-(3-hydroxyphenyl)propylcarbamate 

Relevant academic research and scientific papers

PRODUCTION METHOD FOR OPTICALLY ACTIVE ALCOHOL COMPOUND

A method for stereoselectively producing an optically active alcohol compound. The optically active alcohol compound of Formula (8) can be produced in high yield and high selectivity from the compound of Formula (3), and the production method that is useful industrially and the intermediates therefor can be provided. In formulae, R1 is a hydrogen atom, C1-6 alkyl, C1-6 alkyl optionally substituted with R3, or the like, R2 is cyano or —CH2N(R5)R4, and R3 is C3-8 cycloalkyl.

M-STAGE KINESIN INHIBITOR

A mitotic kinesin Eg5 inhibitor which comprises a thiadiazoline derivative represented by the general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein R1 represents a hydrogen atom and the like, R2 represents a hydrogen atom, -C(=W)R6 (wherein W represents an oxygen atom or a sulfur atom, and R6 represents substituted or unsubstituted lower alkyl and the like) and the like, R3 represents -C(=Z)R19 (wherein Z represents an oxygen atom or a sulfur atom, and R19 represents substituted or unsubstituted lower alkyl and the like) and the like, R4 represents substituted or unsubstituted lower alkyl and the like, and R5 represents substituted or unsubstituted aryl and the like] and the like are provided.