42471-59-0

Basic information

• Product Name: Benzene, 1-broMo-3-(MethoxyMethoxy)-
• Synonyms: Benzene, 1-broMo-3-(MethoxyMethoxy)-;1-BroMo-3-MethoxyMethoxy-benzene
• CAS NO: 42471-59-0
• Molecular Formula: C₈H₉BrO₂
• Molecular Weight: 217.05986
• Mol File: 42471-59-0.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzene, 1-broMo-3-(MethoxyMethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-broMo-3-(MethoxyMethoxy)-(42471-59-0)
• EPA Substance Registry System: Benzene, 1-broMo-3-(MethoxyMethoxy)-(42471-59-0)

Safety Data

• Hazardous Substances Data: 42471-59-0(Hazardous Substances Data)

Usage

General Description

Benzene, 1-bromo-3-(methoxymethoxy)- is an organic compound with the chemical formula C8H9BrO2. It is commonly used as an intermediate in the production of pharmaceuticals and agrochemicals. This chemical is also used in the development of fine chemicals such as dyes, fragrance, and flavor. Benzene, 1-bromo-3-(methoxymethoxy)- is a clear, colorless liquid with a strong odor and it is highly reactive, making it essential to handle with caution. It is considered hazardous and poses health risks if inhaled, ingested, or comes into contact with the skin, as it is a known irritant and may cause harmful effects on the nervous system and organs.

Upstream product

• 13057-17-5 bromethyl methyl ether 
• 591-20-8 3-Bromophenol 
• 3188-13-4 ethyl chloromethyl ether 
• 107-30-2 chloromethyl methyl ether 

Downstream Products

• 491607-99-9 6-(tert-butyldimethylsilanoxyl)-1-(3-methoxymethoxyphenyl)hexan-1-ol 
• 491608-02-7 1-(2-bromo-3-methoxymethoxyphenyl)-6-(tert-butyldimethylsilanyloxy)hexan-1-ol 
• 491607-76-2 6-(tert-butyldimethylsilanoxy)-1-{2-[hydroxy-(8,9,10-trimethoxy-3-methoxymethoxyanthracen-1-yl)methyl]-3-methoxymethoxyphenyl}hexan-1-ol 
• 216443-40-2 3-methoxymethoxyphenylboronic acid 
• 156353-05-8 4-hydroxy-4-[(3-(methyloxymethoxy)phen-1-yl)methyl]tetrahydropyran 
• 25912-16-7 3-(1-pyrrolidinyl)phenol 
• 781675-82-9 tert-butyl {3-[3-(methoxymethoxy)phenyl]-3-oxopropyl}carbamate 
• 1279712-55-8 (R,S)-1-(2'-iodo-3'-(methoxymethoxy)phenyl)-6-(triisopropylsilyloxy)hexan-1-ol 
• 1279712-56-9 (R,S)-2-tert-butyl 1-(1'-(2''-iodo-3''-(methoxymethoxy)phenyl)-6'-(triisopropylsilyloxy)hexyl) 3,8-dimethoxy-9,10-anthraquinone-1,2-dicarboxylate 
• 1279712-54-7 (R,S)-1-(3'-(methoxymethoxy)phenyl)-6-(triisopropylsilyloxy)hexan-1-ol 

Relevant articles and documents

Solvent-mediated tuning of the regioselectivity of intramolecular diaryl ether formation: Total synthesis of (+)-aspercyclide C

A concise total synthesis of the 11-membered cyclic (+)-aspercyclide C is reported. Key to success was the fine-tuning of the reaction media to realize an oxidative, macrocyclic diaryl C-O bond formation in a regioselective and direct fashion.

Palladium-Catalyzed Regioselective Synthesis of 1-Hydroxycarbazoles Under Aerobic Conditions

A palladium-catalyzed aerobic C?H amidation of N-Ts-2-amino-3′-hydroxylbiaryls has been developed to afford a diverse range of 1-hydroxycarbazoles with high regioselectivity and efficiency. This protocol benefits from operational simplicity, robustness, a

CARM1 INHIBITORS AND USES THEREOF

Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula: wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARMl activity. Methods of using the compounds for treating CARMl -mediated disorders are also described.