78174-90-0Relevant academic research and scientific papers
Electrocatalytic Oxidative Hydrofunctionalization Reactions of Alkenes via Co(II/III/IV) Cycle
Liu, Han-Yuan,Mo, Fanyang,Nie, Yi-Chen,Yang, Fan,Zhang, Lei,Zhu, Rong
, p. 2132 - 2137 (2022/02/10)
Here we disclose a general Co(II/III/IV) electrocatalytic platform for alkene functionalization. Driven by electricity, a set of the oxidative hydrofunctionalization reactions via hydrogen atom transfer were demonstrated without the need for stochiometric chemical oxidants. The scope of the reactions encompasses hydroalkoxylation, hydroacyloxylation, hydroarylation, semipinacol rearrangement, and deallylation. Mechanistic studies and stereochemical evidence support an ECEC process involving an electrochemically generated organocobalt(IV) intermediate. This work presents an example of reactivity space expansion in electrocatalysis in the VB12-system by going beyond the common oxidation states of Co(I/II/III).
Hydroalkoxylation of unactivated olefins with carbon radicals and carbocation species as key intermediates
Shigehisa, Hiroki,Aoki, Tatsuya,Yamaguchi, Sumiko,Shimizu, Nao,Hiroya, Kou
supporting information, p. 10306 - 10309 (2013/08/23)
A unique Markovnikov hydroalkoxylation of unactivated olefins with a cobalt complex, silane, and N-fluoropyridinium salt is reported. Further optimization of reaction conditions yielded high functional group tolerance and versatility of alcoholic solvent employed, including methanol, i-propanol, and t-butanol. Use of trifluorotoluene as a solvent made the use of alcohol in stoichiometric amount possible. Mechanistic insight into this novel catalytic system is also discussed. Experimental results suggest that catalysis involves both carbon radical and carbocation intermediates.
REGIOSPECIFIC ALLYLATION OF ACETALS WITH ALLYLSILANES CATALYZED BY IODOTRIMETHYLSILANE. SYNTHESIS OF HOMOALLYLETHERS
Sakurai, Hideki,Sasaki, Koshi,Hosomi, Akira
, p. 745 - 748 (2007/10/02)
Allylation of acetals with allylsilanes is catalyzed by iodotrimethylsilane to give the corresponding homoallyl ethers, with regiospecific transposition of the allyl group.
