78176-87-1Relevant academic research and scientific papers
A One-step Synthesis of Acridines via Palladium(II)-catalysed Ring Formation of Allylated Enaminones
Iida, Hideo,Yuasa, Yoshifumi,Kibayashi, Chihiro
, p. 114 - 115 (1981)
9-Ethyl-3,4,5,6,9,10-hexahydroacridine-1(2H),8(7H)-dione (5) and its N-allyl analogue (6) were formed in a one-step ring-forming reaction from both the 2-and/or N-allyl derivatives of 3-aminocyclohex-2-enone (1) - (4) and from the bisenaminone (7), obtained from the N-allylenaminone (2), on treatment with PdCl2(MeCN)2.
Rapid and Scalable Access into Strained Scaffolds through Continuous Flow Photochemistry
Blanco-Ania, Daniel,Gawade, Sagar Ashok,Zwinkels, Luc J. L.,Maartense, Luuk,Bolster, Marjon G.,Benningshof, Jorg C. J.,Rutjes, Floris P. J. T.
, p. 409 - 413 (2016)
Two conformationally restricted three-dimensional aminoketone scaffolds have been synthesized in only three steps, using a continuous flow photochemistry approach, which is also amenable to scale-up. In addition, several approaches to further derivatize these scaffolds for the synthesis of low molecular weight compound libraries have been detailed.
