78201-99-7Relevant academic research and scientific papers
Studies in Benzofurans: Part X-Syntheses of some Benzopyrimidines and Benzopyrimidobenzothiazole
Vaidya, V.P.,Agasimundin, Y.S.
, p. 114 - 117 (2007/10/02)
Acylation of 3-aminobenzofuran-2-carboxamide using succinic, maleic and phthalic anhydrides under different conditions followed by cyclodehydration of the resultant products (Ia-c) gives 2-substituted-3,4-dihydro-4-oxobenzofuropyrimidines (IIa-c) which on further cyclodehydration furnish new polycyclic heterocycles, 2,3-dihydrobenzofuropyrrolopyrimidine-1,10-dione (IV), benzofuropyrrolopyrimidine-1,10-dione (V) and benzofuroisoindolo(1,7-a>pyrimidine-11,12-dione (VI), respectively.Reaction of ψ-saccharin chloride with 3-aminobenzofuran-2-carboxylic acid derivatives leads to the formation of 2-(o-sulphamoylphenyl)-3,4-dihydro-4-oxobenzofuropyrimidine (VIII) and a new pentacyclic heterocycle 7-oxobenzofuropyrimidobenzothiazole-5,5-dioxide (IX).
