78209-92-4Relevant academic research and scientific papers
PROCESS FOR THE SYNTHESIS OF NON-RACEMIC CYCLOHEXENES
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Page/Page column 46-47; 52, (2021/01/29)
This invention relates to a process for the synthesis of a non-racemic cyclohexene compound of formula (I) by a Diels-Alder reaction of a compound of formula (II) with a compound of formula (III) wherein R11, R22, R33, R44, R55, R66, R77, R88, R99 and Y have the meanings as defined in the description in the presence of a catalyst comprising at least one m-valent metal cation Mm+m+ wherein the metal M is selected from Scandium (Sc), Yttrium (Y), Lanthanum (La), Cerium (Ce), Praseodymium (Pr), Neodymium (Nd), Promethium (Pm), Samarium (Sm), Europium (Eu), Gadolinium 15 (Gd), Terbium (Tb), Dysprosium (Dy), Holmium (Ho), Erbium (Er), Thulium (Tm), Ytterbium (Yb), Lutetium (Lu), Gallium (Ga) and Indium (In), and m is an integer of 1, 2 or 3, and a chiral ligand of the formula (IV) wherein R10a10a, R10b10b, R10c10c, R10d10d, R10a'10a', R10b'10b', R10c'10c', R10d'10d', Z and Z' have the meanings as defined in the description.
An Unprecedented (Semi)Favorskii rearrangement. evidence for the 2-(Acyloxy)cyclopropanones
Sadhukhan, Santu,Baire, Beeraiah
supporting information, p. 1748 - 1751 (2018/04/14)
Discovery and development of an unprecedented (semi)Favorskii rearrangement has been reported. The intermediacy of structurally singular (acyloxy)cyclopropanones has been unraveled by fruitful control experiments including a crossover experiment. This class of cyclopropanones is found to be inert for classical Favorskii functionalization and preferably undergoes a decycloisomerization (ring-chain valence tautomerism) to α-(acyloxy)enones. A cascade conversion of α,α-diiodo-α′-acetoxyketones to (acyloxy)cyclopropanones via α-iodo-α′-acetoxyketones has been achieved by the synchronous dual basicity (Lewis and Br?nsted) of amines. The overall process is found to be very general for diverse substrates and highly efficient.
New Dienophiles: 1-Acetylvinyl Arenecarboxylates. Reactivity toward Cyclopentadiene and Exocyclic Dienes
Tamariz, Joaquin,Vogel, Pierre
, p. 188 - 197 (2007/10/02)
The preparations of 1-acetylvinyl arenecarboxylates H2C=C(COCH3)OCOR with R=phenyl, p-nitrophenyl, 2,4-dinitrophenyl, α- and β-naphthyl are described (3).The Diels-Alder reactivity of these dienophiles toward cyclopentadiene is evaluated and compared with
