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Usage

Uses

Used in Dye Production:
3,6-Pyridazinedicarboxaldehyde is used as an intermediate in the production of various dyestuffs, contributing to the coloration and stability of these products in different applications.
Used in Organic Synthesis:
In the realm of organic synthesis, 3,6-Pyridazinedicarboxaldehyde serves as a reagent, particularly for the formation of heterocyclic compounds, which are essential in creating complex organic molecules with diverse applications.
Used in Pharmaceutical Manufacturing:
3,6-Pyridazinedicarboxaldehyde is utilized in the manufacturing of pharmaceuticals, where it acts as a key component in the synthesis of various medicinal compounds, potentially contributing to the development of new drugs.
Used in Agrochemical Production:
3,6-Pyridazinedicarboxaldehyde is also employed in the production of agrochemicals, where it may be involved in the creation of pesticides or other agricultural chemicals to protect crops and enhance agricultural productivity.
Used in the Synthesis of Functional Materials:
3,6-Pyridazinedicarboxaldehyde is recognized as a versatile building block for the synthesis of various functional materials, indicating its potential applications in the fields of materials science, which could include the development of new materials with specific properties for various industries.
Used in Research and Development:
Due to its potential applications in medicine, agriculture, and materials science, 3,6-Pyridazinedicarboxaldehyde is also used in research and development settings to explore new methods of synthesis and to discover its further applications.
It is crucial to handle 3,6-Pyridazinedicarboxaldehyde with care due to its flammable nature and potential hazards, ensuring safety in its use and production.

Upstream product

• 37444-30-7 3,6-bis(hydroxymethyl)pyridazine 
• 1632-74-2 3,6-dimethylpyridazine 
• 1883-75-6 2,5-bis-(hydroxymethyl)furan 
• 2166-24-7 pyridazine-3,6-dicarboxylic acid dimethyl ester 
• 58488-28-1 Acetic acid 6-acetoxymethyl-pyridazin-3-ylmethyl ester 
• 110-13-4 2,5-hexanedione 
• 37444-27-2 Acetic acid 5-acetoxymethyl-2,5-dimethoxy-2,5-dihydro-furan-2-ylmethyl ester 
• 5076-10-8 2,5-bis(hydroxymethyl)furan diacetate 

Downstream Products

• 177650-54-3 3,6-bis-(hydroximinomethyl)pyridazine 
• 752994-89-1 (2-pyridin-2-yl-ethyl)-{6-[(2-pyridin-2-yl-ethylamino)-methyl]-pyridazin-3-ylmethyl}-amine 

Relevant academic research and scientific papers

Synthesis and structure of dilead(II) and dimanganese(II) complexes of macrocycles derived from 3,6-diformylpyridazine

An improved synthesis of 3,6-diformylpyridazine I has been elaborated. The macrocyclic complexes Pb2L1(ClO4)4 1 and [Pb2L2][ClO4]4 2 were prepared from this precursor, 1,3-diaminopropane and lead(II) perchlorate in 1:1:1 and 2:2:1 ratios respectively. The ability of lead(II) perchlorate to template the formation of the two macrocycle ring sizes, L1 = (2 + 2) and L2 = (4 + 4), simply by alteration of the reagent ratio is unprecedented. Transmetallation of 1 or 2 with manganese(II) perchlorate and an excess of sodium thiocyanate led to the formation of [Mn2L1(NCS)4] 3. Single-crystal X-ray analyses of 2 and 3 revealed that on transmetallation a ring contraction, (4 + 4) to (2 + 2), occurs. The two manganese(II) ions have irregular geometries and are inequivalent; one is six- whilst the other is seven-co-ordinate. Unusual single-atom > NCS bridging of the manganese ions occurs.

Redox rich dicobalt macrocycles as templates for multi-electron transformationsf

Pyridazine-templated dicobalt macrocycles reversibly support five oxidation states with unusually positive CoII/CoI redox couples, and are also active proton reduction electrocatalysts. The Royal Society of Chemistry 2009.

Synthesis of 3,6-Disubstituted Pyridazine Derivatives

The synthesis of pyridazine functionalized with dioximes side chains are described. Several 3,6-disubstituted pyridazine derivatives were prepared and their structures determined by spectroscopic methods (nmr, ir and ms).

Dicopper(II) Complexes of Novel Polyfunctional Pyridazines: Crystal Structure and Magnetic Properties of Bis1,N':N2,N">-bis

Two novel pyridazine ligands with 3,6-CR=NOH (R = H, H2L1; Ph, H2L2) oxime side chains were synthesised. the related copper(II) dinuclear complexes 1)2(ClO4)2(H2O)2> 1 and 2)2(ClO4)2(MeOH)n> 2 were obtained subsequently.The crystal structure of 1 was determined: space group P21/n, a=12.031(6), b=9.517(4), c=9.973(5) Angstroem, β=100.16 deg and Z=2.The copper(II) ions of the binuclear unit are bridged by the two diazine fragments of the two essentially planar tetradentate ligands with the oxime nitrogen atoms completing the equatorial co-ordination.Two intra-complex hydrogen bridges link the terminal oximato moieties to give dinucleating macrocyclic complexes.In complexes 1 and 2 the copper(II) is in a classical 4 + 2 environment.The magnetic properties of those compounds revealed a spin-singlet ground state in each case.The singlet-triplet energy gaps were found to be -536(2) for 1 and -545(4) cm-1 for 2.The low-lying states of the complexes are discussed in relation to the nearly planar structure of the macrocyclic complexes.

Poly[di-1,2-(diazinylidene)-ethene-1,2-diols]

Poly[di-1,2-(diazinylidene)-ethene-1,2-diols] having the structure: in which the C4 H2 N2 group is a diazinylidene diradical having each C(OH) group adjacent (ortho) to one but not two ring nitrogen atoms and not adjacent (ortho) to each other; X and Y are terminal formyl (CHO) groups or groups derived from them by oxidation; and n has a value of zero to seven--are prepared by a cyanide ion catalyzed condensation of pyrazine-2,5-dicarboxaldehyde, pyridazine-3,6-dicarboxaldehyde; or pyrimidine-4,6-dicarboxaldehyde as the only aldehydes which provide the requisite structures. The polymers form complexes with metal ions including manganese, which is insoluble, and vanadium, which is soluble.