78235-07-1Relevant academic research and scientific papers
Site-Selective Linear Alkylation of Anilides by Cooperative Nickel/Aluminum Catalysis
Okumura, Shogo,Komine, Takuya,Shigeki, Erika,Semba, Kazuhiko,Nakao, Yoshiaki
supporting information, p. 929 - 932 (2017/12/26)
We report meta- and para-selective linear alkylation reactions of anilides with alkenes by nickel/N-heterocyclic carbene (NHC) and aluminum catalysis. With a less bulky NHC, the alkylation reaction of N-methyl-N-phenylcyclohexanecarboxamides proceeded mainly at the meta position. In contrast, a bulky NHC ligand led to the para-selective alkylation of N-sec-alkyl anilides.
Benzamide derivatives and uses related thereto
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Page/Page column 46-47, (2008/06/13)
Benzamide derivatives of formulae I and II, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof, and pharmaceutical compositions comprising the same, are described and have therapeutic utility, particularly in the treatment of diabetes, obesity, and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are defined as provided herein.
TACHYKININ RECEPTOR ANTAGONISTS
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Page 59, (2010/02/10)
The present invention relates to selective NK-1 receptor antagonists of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of disorders associated with an excess of tachykinins.
Process for the preparation of N-alkylhalogenoanilines
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, (2008/06/13)
A process for the preparation of N-alkylhalogenoanilines of the formula (I) 100° STR1 in which X is a chlorine or bromine atom and n is the number 1 or 2, R1 is an alkyl (C1 -C4) radical, R2 an alkyl (C1/s
