782479-35-0Relevant academic research and scientific papers
Structural revision and total synthesis of azaspiracid-1, part 2: Definition of the ABCD domain and total synthesis
Nicolaou,Koftis, Theocharis V.,Vyskocil, Stepan,Petrovic, Goran,Ling, Taotao,Yamada, Yoichi M. A.,Tang, Wenjun,Frederick, Michael O.
, p. 4318 - 4324 (2004)
The chase for the structure of azaspiracid-1 has ended with a revised structure (see picture). The total synthesis of this challenging target has closed another chapter in this intriguing chemical detective story and allowed the assignment of the relative
Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1
Nicolaou,Koftis, Theocharis V.,Vyskocil, Stepan,Petrovic, Goran,Tang, Wenjun,Frederick, Michael O.,Chen, David Y.-K.,Li, Yiwei,Ling, Taotao,Yamada, Yoichi M. A.
, p. 2859 - 2872 (2007/10/03)
The molecular structure of azaspiracid-1, a neurotoxin isolated from mussels, has been elucidated by total synthesis which also enriched its supplies. The degradatively derived fragments of this marine biotoxin, compounds 5 (EFGHI), 6 (FGHI), and 40 (ABCD
