782479-81-6Relevant articles and documents
Stereochemical Feature of Palladium(II)-Catalyzed Claisen Rearrangement
Sugiura, Masaharu,Nakai, Takeshi
, p. 697 - 698 (1995)
The title rearrangements of the geometrical isomers of crotyl enol ethers are shown to exhibit the identical anti diastereoselection, in contrast to the high stereospecificity observed in the thermal rearrangements.These outcomes are discussed on mechanistic grounds.
gamma-alkenyl ketone and preparation method thereof
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Paragraph 0031; 0124-0127, (2020/02/29)
The invention discloses a gamma-alkenyl ketone preparation method, wherein the target product can be obtained at high yield and high regioselectivity by using acetophenone and 1,3-butadiene as raw materials in the presence of an organic solvent, a catalyst, an additive and a ligand. According to the invention, the method has advantages of high atom economy, high regioselectivity, high yield and the like, can achieve the efficient conversion from a cheap basic organic chemical product 1,3-butadiene to high-added-value gamma-alkenyl ketone, and uses the cheap catalyst, so that the reaction conditions are neutral and mild, and the experimental operation is safe and simple; and the synthesized gamma-alkenyl ketone is a useful synthetic intermediate, can be subjected to a series of conversionsto obtain a series of drug molecule precursors or key intermediates, and has wide application prospect.
Convenient Radical α-Monoallylations of Carbonyl Compounds
Watanabe, Yoshihiko,Yoneda, Tetsuo,Okumura, Tatsuya,Ueno, Yoshio,Toru, Takeshi
, p. 3030 - 3033 (2007/10/02)
Free radical allylations of α-seleno carbonyl compounds with tributyl-substituted 2,4-pentadienyltin, 2-methyl-2-propenyltin, 2-butenyltin, and 3-methyl-2-butenyltin, are described. Such successful C-C bond formations, in particular with the 2-butenyltin and the 3-methyl-2-butenyltin, are owing to the high reactivity of the α-carbon radical, generated from α-seleno carbonyl compounds, toward allylic tin compounds.
