782493-43-0

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 4-[3-[[(4-methylphenyl)sulfonyl]oxy]-5-isoxazolyl]-, 1,1-dimethylethyl ester
• CAS NO: 782493-43-0
• Molecular Formula: C20H26N2O6S
• Molecular Weight: 422.502
• Mol File: 782493-43-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 4-[3-[[(4-methylphenyl)sulfonyl]oxy]-5-isoxazolyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 4-[3-[[(4-methylphenyl)sulfonyl]oxy]-5-isoxazolyl]-, 1,1-dimethylethyl ester(782493-43-0)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 4-[3-[[(4-methylphenyl)sulfonyl]oxy]-5-isoxazolyl]-, 1,1-dimethylethyl ester(782493-43-0)

Safety Data

• Hazardous Substances Data: 782493-43-0(Hazardous Substances Data)

Upstream product

• 782493-41-8 5-(piperidin-4-yl)isoxazol-3-ol hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 782493-42-9 tert-butyl 4-(3-hydroxyisoxazol-5-yl)piperidine-1-carboxylate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 782493-39-4 5-piperidin-4-ylisoxazol-3-yl 4-methylbenzenesulfonate hydrochloride 

Relevant articles and documents

BENZOXAZINYL-AMIDOCYCLOPENTYL-HETEROCYCLIC MODULATORS OF CHEMOKINE RECEPTORS

Cyclopentyl compounds linked to a benzoxazinyl group through an amido moiety utilizing the ring nitrogen of the benzoxazine, and further substituted with a heterocyclic moiety, such compounds represented by formula I: which are used to modulate the CCR-2 chemokine receptor to prevent or treat inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis; and pharmaceutical compositions comprising these compounds and the use of these compounds and compositions.