78311-98-5Relevant articles and documents
Synthesis and biological evaluation of analogues of butyrolactone I and molecular model of its interaction with CDK2.
Brana, Miguel F,Garcia, M Luisa,Lopez, Berta,de Pascual-Teresa, Beatriz,Ramos, Ana,Pozuelo, Jose M,Dominguez, M Teresa
, p. 1864 - 1871 (2007/10/03)
A series of analogues of butyrolactone I, a natural product isolated from Aspergillus terreus that selectively inhibits the CDK2 and CDK1 kinases and that has been found to exhibit an interesting antiproliferative activity, have been synthesized. Its anti