78312-49-9

Basic information

• Product Name: 14β-benzyloxycarbonylaminocodeinone
• CAS NO: 78312-49-9
• Molecular Weight: 446.503
• Mol File: 78312-49-9.mol

Chemical Properties

• CAS DataBase Reference: 14β-benzyloxycarbonylaminocodeinone(CAS DataBase Reference)
• NIST Chemistry Reference: 14β-benzyloxycarbonylaminocodeinone(78312-49-9)
• EPA Substance Registry System: 14β-benzyloxycarbonylaminocodeinone(78312-49-9)

Safety Data

• Hazardous Substances Data: 78312-49-9(Hazardous Substances Data)

Upstream product

• 68617-37-8 14β-aminocodeinone dimethyl acetal 
• 68617-45-8 14β-nitrocodeinone dimethyl acetal 
• 115-37-7 thebaine 
• 501-53-1 benzyl chloroformate 
• 68615-94-1 14β-aminocodeinone 

Relevant articles and documents

The Nitration of Thebaine with Tetranitromethane

Thebaine (1) reacts in methanol with tetranitromethane to give, as major product, 14β-nitrocodeinone dimethyl acetal (2a), which has been converted into, inter alia, 14β-nitrocodeinone (3a), 14β-aminocodeinone dimethyl acetal (2b), 14β-aminocodeinone (3b), and 14β-aminocodeine.The nitration of thebaine with tetranitromethane in benzene in the presence of oxygen takes a different course.The major product has been identified as the cyclic peroxide 8α,10α-epidioxy-8,14-dihydro-14β-nitrothebaine (5) by a series of degradations leading to new 10α-hydroxy- and 10-oxo-thebaine derivatives.