Journal of the Chemical Society. Perkin transactions I p. 1143 - 1147 (1981)
Update date:2022-08-02
Topics:
Allen, Robert M.
Kirby, Gordon W.
McDougall, David J.
Thebaine (1) reacts in methanol with tetranitromethane to give, as major product, 14β-nitrocodeinone dimethyl acetal (2a), which has been converted into, inter alia, 14β-nitrocodeinone (3a), 14β-aminocodeinone dimethyl acetal (2b), 14β-aminocodeinone (3b), and 14β-aminocodeine.The nitration of thebaine with tetranitromethane in benzene in the presence of oxygen takes a different course.The major product has been identified as the cyclic peroxide 8α,10α-epidioxy-8,14-dihydro-14β-nitrothebaine (5) by a series of degradations leading to new 10α-hydroxy- and 10-oxo-thebaine derivatives.
View MoreContact:+86-579-85206992
Address:No 451 chouzhou north road ,room 1106 int'l business center , yiwu ,china
Fujian Huitian Biological Pharmacy Co., Ltd.
Contact:0086-598-8300831; 8339920
Address:No.46,Taijiang Road,Sanming City,Fujian,China
Xi'an HO-SHINE Bio-Technology Co., Ltd
Contact:+86 (29) 8248-5435/18292020086
Address:No.6 Shiyuan Road Xian City Shaanxi Province, 710048 China
Hubei Onward Bio-Development Co., Ltd.
Contact:+86-718-8417012
Address:No.517,Shizhou Avenue,Enshi City,Hubei Province,China,445002
SuZhou Bichal Biological Technology CO.,LTD
Contact:+86-512-68051130
Address:NO.32 huoju road HI-TECH Industrial development zone SuZhou China
Doi:10.1016/j.ejps.2006.05.010
(2006)Doi:10.1021/jm00310a047
(1968)Doi:10.1081/NCN-200060173
(2005)Doi:10.1081/NCN-200060085
(2005)Doi:10.1081/NCN-200060244
(2005)Doi:10.1016/j.ejmech.2006.03.005
(2006)
