783349-63-3

Upstream product

• 783349-62-2 6-chloro-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride 
• 98-88-4 benzoyl chloride 

Downstream Products

• 783349-64-4 2-benzoyl-6-chloro-2,3,4,9-tetrahydro-1H-β-carbolin-4-one 

Relevant academic research and scientific papers

Beta-carbolines useful for treating inflammatory disease

This invention provides beta-carboline compounds of formula III-A-aa: wherein Q, G, R1, R2, R3, and R6b are as described in the specification. The compounds are useful for treating diseases such as inflammatory diseases and cancer.

BETA-CARBOLINES USEFUL FOR TREATING INFLAMMATORY DISEASE

This invention provides beta-carboline compounds of formula (I) wherein Ring A is a substituted pyridinyl, pyrimidinyl, morpholinyl, piperidinyl, piperazinyl, pyrrolidinyl, pyranyl, tetrahydrofuranyl, cyclohexyl, cyclopentyl or thiomorpholinyl ring and R1, R2 and R3 are as described in the specification. The compounds are IKK-2 inhibitors that are useful for treating IKK-2 mediated diseases such as inflammatory diseases and cancer.