783357-29-9

Basic information

• Product Name: (R)-(-)-2-N-formylamino-butyric acid
• CAS NO: 783357-29-9
• Molecular Weight: 131.131
• Mol File: 783357-29-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-(-)-2-N-formylamino-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-2-N-formylamino-butyric acid(783357-29-9)
• EPA Substance Registry System: (R)-(-)-2-N-formylamino-butyric acid(783357-29-9)

Safety Data

• Hazardous Substances Data: 783357-29-9(Hazardous Substances Data)

Upstream product

• 64-18-6 formic acid 
• 2623-91-8 (R)-2-aminobutyric acid 

Relevant articles and documents

Synthesis of chiral pentacyclo-undecane ligands and their use in the enantioselective alkylation of benzaldehyde with diethylzinc

The synthesis of a new class chiral cage annulated bidentate ligands is reported. The ability of the chiral amino alcohols to catalyse the enantioselective addition of diethyl zinc to benzaldehyde was investigated. The cage annulated amino alcohols have C1 symmetry and showed poor to good enantioselectivity with high chemical yields. The system could be utilised as a versatile probe into the reaction mechanism. The synthesis of a new class of chiral pentacycloundecane cage annulated bidentate ligands is reported. This class of ligands can be used in many reactions that are catalysed by amino alcohol ligands. The ability of the chiral ligands to asymmetrically catalyse the reaction between diethylzinc and benzaldehyde was investigated. The cage annulated bidentate ligands have C1 symmetry and showed poor to good enantioselectivity with high yields compared to previous systems reported using other amino alcohol ligands. An important conclusion from the results is that both ligands should be involved in the mechanism as the bidentate ligands gives much improved enantioselectivity when compared with a single chiral source molecule. This system could be utilised as a versatile probe for examining the reaction mechanism.