78349-03-8

Basic information

• Product Name: 2-(1-hydroxy-1-phenylethyl)-1,3-dithiane
• Synonyms: 2-(1-hydroxy-1-phenylethyl)-1,3-dithiane
• CAS NO: 78349-03-8
• Molecular Weight: 240.39
• Mol File: 78349-03-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(1-hydroxy-1-phenylethyl)-1,3-dithiane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-hydroxy-1-phenylethyl)-1,3-dithiane(78349-03-8)
• EPA Substance Registry System: 2-(1-hydroxy-1-phenylethyl)-1,3-dithiane(78349-03-8)

Safety Data

• Hazardous Substances Data: 78349-03-8(Hazardous Substances Data)

Upstream product

• 13411-42-2 2-(trimethylsilyl)-1,3-dithiane 
• 98-86-2 acetophenone 
• 505-23-7 1,3 dithiane 
• 78350-65-9 (S(CH₂)3S)CHTi(OCH(CH₃)2)3 
• 36049-90-8 2-lithio-1,3-dithiane 

Downstream Products

• 4361-50-6 2-hydroxy-2-phenyl-propionaldehyde 
• 840522-77-2 2-(1-phenyl-1-prop-2-ynyloxy-ethyl)-[1,3]dithiane 
• 840522-91-0 2-(2-oxo-propoxy)-2-phenyl-propionaldehyde 
• 840522-90-9 2-phenyl-2-prop-2-ynyloxy-propionaldehyde 

Relevant articles and documents

Novel synthesis of a 1,3,5-trioxazatriquinane skeleton using a nitrogen clamp

(Chemical Equation Presente) An α-hydroxyaldehyde derived from naltrexone was converted to an oxazoline dimer with ammonium chloride and sodium acetate in MeOH under reflux. The resulting dimer was treated with dl-camphorsulfonic acid in CHCl3 to give the trimer. The method for trimer synthesis was also applied to general α-hydroxyaldehydes to afford trimers in good yield.

Mercury(II) chloride-mediated cyclization - Rearrangement of O-propargylglycolaldehyde dithioacetals to 3-pyranone dithioketals: An expeditious access to 3-pyranones

(Chemical Equation Presented) O-Propargyl glycolaldehyde dithioacetals undergo a unique cyclization-rearrangement in the presence of mercuric chloride and calcium carbonate to afford 3-pyranones exclusively or along with 2,5-dihydrofuran-3-carboxaldehydes

Selectivities in the Reactions of Alkyl-, Aryl- and Heterosubstituted Organotitanium Compounds

Solutions of the title compounds R-Ti(OR')3 (1) are generally available from organolithium (or magnesium) derivatives according to equation 1.It is shown (table 1) that some heterosubstituted organotitanium compounds are more stable thermally than their lithium counterparts.The reagents 1 are highly selective carbonylophiles (Tables 1 and 2), their reactivity can be modified by variation of the R'O-group (Table 3) and with the chiral (S)-2-methyl-1-butoxy group an enantioselective addition can be achieved.