78370-23-7

Upstream product

• 91600-48-5 benzoyloxyimino-p-tolyl-acetonitrile 
• 7664-93-9 sulfuric acid 
• 2947-61-7 (4-methylphenyl)acetonitrile 
• 110-46-3 isopentyl nitrite 
• 86329-42-2 4-p-tolyl-furazan-2-oxide 
• 64-17-5 ethanol 
• 64-19-7 acetic acid 
• 10349-07-2 p-Tolyl-furazan 
• 7732-18-5 water 

Downstream Products

• 7163-50-0 (4-methylphenyl)(oxo)acetic acid 
• 91600-48-5 benzoyloxyimino-p-tolyl-acetonitrile 

Relevant academic research and scientific papers

Arylglyoxylic acid as well as preparation method and application thereof

The invention relates to arylglyoxylic acid as well as a preparation method and application thereof, and the method comprises the following steps: carrying out hydrolysis reaction on arylglyoxylonitrile oxime as shown in a formula (I) under the catalysis of an inorganic acid to obtain arylglyoxylic acid as shown in a formula (II). The arylglyoxylic acid prepared by the preparation method is high in yield, high in product purity, simple to operate, environment-friendly and pollution-free. The arylglyoxylic acid is used as a fine chemical synthesis intermediate.

Cu-Mediated Stereoselective [4+2] Annulation between N-Hydroxybenzimidoyl Cyanide and Norbornene

A Cu-mediated stereoselective [4+2] annulation between N-hydroxybenzimidoyl cyanides and norbornene (NBE) has been developed for the synthesis of 4H-1,2-oxazin-4-ones. The reaction proceeds through sequentially forming C-O/C-C bonds. The advantage of this reaction includes high stereoselectivity, excellent yields, as well as simple and mild reaction conditions. A total of 26 examples are presented along with some control experiments.