78376-73-5

Upstream product

• 154-23-4 catechin 
• 51079-25-5 (2R,3S)-(+)-catechin 3',4',5,7-tetramethyl ether 
• 51196-02-2 5,7,3',4'-tetra-O-methylepicatechin 
• 490-46-0 (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 
• 186581-53-3 diazomethane 
• 88038-00-0 6,8-dibromo-(-)-epicatechin 
• 77-78-1 dimethyl sulfate 
• 88488-98-6 (2R,3S)-6,8-Dibromo-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol 

Downstream Products

• 78376-74-6 6,8-dibromo-3-O-acetyl-3',4',5,7-tetra-O-methyl-(-)-epicatechin 
• 78376-75-7 3-O-benzyl-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 69119-49-9 3-O-acetyl-6-methoxycarbonyl-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 69119-43-3 6-bromo-3-O-acetyl-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 78393-95-0 6-bromo-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 23671-72-9 8-bromo-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 69119-53-5 8-acetoxy-3-O-benzyl-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 69119-56-8 3-O-benzyl-8-methoxycarbonyl-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 69119-46-6 6-acetoxy-3-O-benzyl-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 69119-47-7 3-O-benzyl-6-methoxycarbonyl-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 28699-20-9 3-O-benzyl-8-bromo-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 69119-51-3 3-O-benzyl-8-hydroxy-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 69119-40-0 6-bromo-3',4',5,7-tetra-O-methyl-(+)-catechin 
• 69119-44-4 3-O-benzyl-6-hydroxy-3',4',5,7-tetra-O-methyl-(+)-catechin 

Relevant academic research and scientific papers

Ecofriendly synthesis of halogenated flavonoids and evaluation of their antifungal activity

Brominated and chlorinated flavonoids belonging to different classes (flavanones, flavones and catechins) were prepared from the corresponding flavonoids by a simple and ecofriendly procedure based on the use of sodium halides, aqueous hydrogen peroxide and acetic acid. Pure samples of substrates and products were tested against Trichoderma koningii, Fusarium oxysporum and Cladosporium cladosporioides, common saprotrophic soil and seed fungi, potential pathogens for humans and their activity was expressed as linear mycelial growth inhibition (%). Among them, 8-chloro-5,7,3′,4′-tetramethoxyepicatechin 29, a novel catechin derivative, exhibited a remarkable effect against all tested fungi also at low concentrations.

Synthesis of Condensed Tannins. Part 12. Direct Access to - and -all-2,3-cis-Procyanidin Derivatives from (-)-Epicatechin: Assessment of Bonding Positions in Oligomeric Analogues from Crataegus oxyacantha L.

Synthesis of methyl ester acetates of - and -all-2,3-cis-procyanidin biflavanoids is effected by oxidative functionalization of (-)-epicatechin tetramethyl ester with lead tetra-acetate, and condensation of the resultant 2,3-cis-flavan-3,4-diol

Electrophilic Aromatic Substitution of Catechins: Bromination and Benzylation

Relative yields of C-6, C-8, and C-6 and C-8 substituted catechins obtained from the reaction of (+)-catechin or 3',4',5,7-tetra-O-methyl-(+)-catechin with pyridinium hydrobromide-perbromide, bromine, p-hydroxybenzyl alcohol, or o-hydroxybenzyl alcohol sh

Synthesis of Condensed Tannins. Part 3. Chemical Shifts for Determining the 6- and 8-Bonding Positions of 'Terminal' (+)-Catechin Units

Pairs of 6- and 8-functionalised (Br, OH, OAc, CO2Me, and CH2Me groups) 3',4',5,7-tetra-O-methyl-(+)-catechins available through selective bromination and debromination reactions and hence via lithio-analogues, provide diagnostic chemical shifts of their