78380-61-7

Basic information

• Product Name: Cyclobutanecarbonitrile, 3-(1-pyrrolidinyl)-, cis- (9CI)
• Synonyms: Cyclobutanecarbonitrile, 3-(1-pyrrolidinyl)-, cis- (9CI);cis-3-(1-Pyrrolidinyl)cyclobutanecarbonitrile
• CAS NO: 78380-61-7
• Molecular Formula: C9H14N2
• Molecular Weight: 150.22086
• Product Categories: PYRROLIDINE
• Mol File: 78380-61-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 260℃
• Flash Point: 107℃
• Appearance: /
• Density: 1.06
• CAS DataBase Reference: Cyclobutanecarbonitrile, 3-(1-pyrrolidinyl)-, cis- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclobutanecarbonitrile, 3-(1-pyrrolidinyl)-, cis- (9CI)(78380-61-7)
• EPA Substance Registry System: Cyclobutanecarbonitrile, 3-(1-pyrrolidinyl)-, cis- (9CI)(78380-61-7)

Safety Data

• Hazardous Substances Data: 78380-61-7(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 16955-35-4 1-cyanobicyclo<1.1.0>butane 
• 78403-00-6 3-pyrrolidinocyclobutane-1-carbonitrile 

Relevant articles and documents

Addition to bicyclobutane derivatives. IV. Stereochemistry of the addition of secondary amines to bicyclobutane-1-carbonitrile and 3-methylbicyclobutane-1-carbonitrile

Secondary amines (dimethylamine, diethylamine, pyrrolidine, piperidine, and morpholine) add to bicyclobutane-1-carbonitrile and 3-methylbicyclobutane-1-carbonitrile exclusively at the central C-C bond with nucleophilic attack at the β position in relation to the nitrile group.The reactions are not stereospecific, but they are all cis-stereoselective.It was found that the structure of the substrate and the reagent and also the nature of the solvent have effects on the stereochemistry of addition.