78411-47-9Relevant academic research and scientific papers
STEREOSPECIFIC ALKYLATION OF THE OXIDIZED DIKETOPIPERAZINE DERIVATIVE. 3,6-DIMETHOXY-1,4-DIMETHYL-2,5-PIPERAZINEDIONE
Nakatsuka, Shin-ichi,Sasaki, Kenji,Yamaguchi, Ken-ichiro,Goto, Toshio
, p. 695 - 696 (2007/10/02)
Kinetic monoalkylation of 3,6-dimethoxy-1,4-dimethyl-2,5-piperazinedione 2a via its anion gave a single stereoisomer (3) in which two methoxy groups are in the same side.Acid catalyzed equilibrium of 3 gave a mixture of 3 and its stereoisomer 4 in about 1:1 ratio.Acylation also gave a monoacylated product.
