784155-54-0

Basic information

• Product Name: N-(5-FLUORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE
• Synonyms: N-(5-FLUORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE;Propanamide, N-(5-fluoro-2-pyridinyl)-2,2-dimethyl- (9CI);N-(5-fluoropyridin-2-yl)pivalaMide
• CAS NO: 784155-54-0
• Molecular Formula: C10H13FN2O
• Molecular Weight: 196.2214232
• Product Categories: PYRIDINE
• Mol File: 784155-54-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 333.316°C at 760 mmHg
• Flash Point: 155.384°C
• Appearance: /
• Density: 1.158g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: N-(5-FLUORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-FLUORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE(784155-54-0)
• EPA Substance Registry System: N-(5-FLUORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE(784155-54-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 784155-54-0(Hazardous Substances Data)

Usage

General Description

N-(5-Fluoro-pyridin-2-yl)-2,2-dimethyl-propionamide is a chemical compound with the molecular formula C12H15FN2O. It is a white solid with a molecular weight of 218.26 g/mol. N-(5-FLUORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also used as a reagent in organic chemistry reactions. The chemical structure of N-(5-Fluoro-pyridin-2-yl)-2,2-dimethyl-propionamide contains a fluorine atom, a pyridine ring, and a dimethyl-propionamide group, which gives it its unique chemical properties and reactivity. Due to its diverse applications, this compound is important in the field of medicinal chemistry and chemical synthesis.

InChI:InChI=1/C10H13FN2O/c1-10(2,3)9(14)13-8-5-4-7(11)6-12-8/h4-6H,1-3H3,(H,12,13,14)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 21717-96-4 2-amino-5-fluoropyridine 
• 31301-51-6 2-chloro-5-fluoropyridine 

Downstream Products

• 1188433-88-6 2-amino-5-fluoropyridine-3-carbaldehyde 
• 1188431-89-1 2-(6-fluoro-2-trifluoromethyl-[1,8]-naphthyridine-3-carbonyl)cyclohexane-1,3-dione 
• 1188433-81-9 N-(5-fluoro-3-formylpyridin-2-yl)-2,2-dimethylpropanamide 
• 823218-50-4 N-(5-fluoro-3-iodo-pyridin-2-yl)-2,2-dimethyl-propionamide 

Relevant articles and documents

NOVEL TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES

The present invention is directed to tricyclic compounds of formula (I), (Ia) or (Ib) which are inhibitors of one or more mutant IDH enzymes. The present invention is also directed to uses of these tricyclic compounds in the potential treatment or prevention of cancers in which one or more mutant IDH enzymes are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such cancers.

HERBICIDAL COMPOUNDS

The present invention relates to novel herbicidal oxopyridine and thionopyridine derivatives of Formula (I), or an agronomically acceptable salt of said compound wherein R1, R5, R6, R7, X1, X2/s

HETEROCYCLIC BENZODIAZEPINE CGRP RECEPTOR ANTAGONISTS

Compounds of formula I: (where variables R2, R7, D, W, X, Y and Z are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.