784193-20-0

Upstream product

• 97-51-8 5-Nitrosalicylaldehyde 
• 100-02-7 4-nitro-phenol 
• 24590-01-0 acetyloxy(2-acetyloxy-5-nitrophenyl)methyl acetate 

Downstream Products

• 578710-63-1 N,N'-ethylenebis(salicylideneiminato)iron(II) 
• 14167-18-1 salcomine 
• 1166842-07-4 C₂₆H₃₄N₄O₆ 
• 402826-43-1 tert-butyl (3-formyl-4-hydroxyphenyl)carbamate 

Relevant academic research and scientific papers

Film polymerization - A new route to the synthesis of insoluble polyimides containing functional nickel(II) Schiff base units in the main chain

The synthesis and characterization of a new, amino-derivatized functional bis(salicylaldiminato)NiII complex is reported. It is a useful and reactive precursor in the synthesis of polyimide thermosets. Thus, the first synthesis of a polyimide c

Magnetic substance and magnetic substance manufacturing method

[object] A magnetization technique that enhances magnetic properties of an organic compound is provided without damaging properties of the organic compound or while maintaining the structure of the organic compound. [solution] The present disclosure is a method for manufacturing a magnetic substance composed of crystals of a magnetization target compound and an electron acceptor by combining the magnetization target compound with the electron acceptor; forming a solution by dissolving a mixture of the magnetization target compound and the electron acceptor in a solvent; maintaining the solution in a very low temperature state and allowing the solution to deposit the crystals of the magnetic target compound and the electron acceptor; and separating the crystals from the solvent.

ANTI-CANCER AGENT AND CANCER CELL KILLING METHOD

[Object] An anticancer agent capable of continuously killing cancer cells in a plurality of phases is provided. [Solution] An anticancer agent contains a complex produced by making a metal-salen complex compound, which includes a central metal and (N, N,

IRON-SALEN COMPLEX

The present invention provides a drug delivery system that overcomes conventional technical problems and that is readily put to practical use. Iron-salen complexes represented by General Formula (I) below. The invention renders iron-salen complexes magnetic, which can thus be used as drugs that can be delivered to affected areas in the body using the inherent magnetic properties of the drug without employing carriers composed of magnetic substances as has been done hitherto.

MAGNETIC SUBSTANCE

The present disclosure relates to a ferromagnetic substance containing a crystal of a metal complex molecule in which a heterocycle is bonded to metal, the metal of the metal complex molecule is bonded to the metal of another metal complex via oxygen as a electron donor, and the ferromagnetic substance has a ferromagnetic property balanced with stability of crystals based on a metal—electron donor—metal bond angle that is from 130° to 160°. The present disclosure also relates to a drug containing, as a principal component, the crystal of the metal complex molecule.

Iron-salen complexes, magnetic drug, chemical induction system, and a magnetic detecting device

PROBLEM TO BE SOLVED: To realize, by solving technical problems of the prior art, a drug delivery system which can be easily implemented practically.SOLUTION: The provided iron-salen complex is expressed by the following formula (1). Since the iron-salen complex per se can potentially be magnetic, it becomes possible, in a case where the same is used as a pharmaceutical, to guide the pharmaceutical to an affected site inside a patient's body by taking advantage of the magnetic property borne by the pharmaceutical per se without using carriers consisting of magnets, as in the prior art.

AUTO-MAGNETIC METAL SALEN COMPLEX COMPOUND

The molecular structures of metal-salen complexes which exerts pharmacological effects are clarified and the metal-salen complexes having such molecular structures and their derivatives are provided. A metal-salen complex compound is characterized in that a metal atom part in each of multiple molecules of the metal-salen complex or its derivative is multimerized via water.

METAL SALEN COMPLEX COMPOUND, LOCAL ANESTHETIC, AND ANTI-MALIGNANT TUMOR AGENT

A metal-salen complex compound, which exhibits excellent noninvasiveness and can be efficiently transferred to an affected site, a local anesthetic containing this metal-salen complex compound, and an antineoplastic drug containing this metal-salen complex compound are provided. Regarding the metal-salen complex compound, a metal atom part in each of two molecules of a metal-salen complex or a derivative of the metal-salen complex is dimerized via water, and the metal-salen complex compound is mixed with a base to produce an ointment.

MAGNETIC COMPOSITION, AND METHOD FOR PRODUCING SAME

A magnetic composition containing a metal-salen complex compound which can be securely guided by a magnetic field to a target area to be preferably treated, and a method for producing the magnetic composition are provided. The magnetic composition is prepared by dispersing magnetic particles, which are obtained by coating a metal-salen complex compound with a dispersant, in a polar solvent by means of the dispersant. Furthermore, the magnetic composition production method includes a first step of mixing the metal-salen complex compound with the dispersant in an organic solvent and coating the metal-salen complex compound with the dispersant and a second step of dispersing the metal-salen complex in a polar solvent.

ANTI-BRAIN-TUMOR DRUG

A drug containing a metal-salen complex compound which is effective for a brain tumor is provided. The present invention is an anti-brain-tumor drug containing a metal-salen complex compound represented by the following Chemical Formula (I). In the formula, M represents a metal atom which is Fe, Cr, Mn, Co, Ni, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu, or Gd, and X represents a halogen atom.