78423-49-1

Basic information

• Product Name: Benzaldehyde, 2,4,6-trihydroxy-3-(3-methyl-1-oxobutyl)-
• CAS NO: 78423-49-1
• Molecular Formula: C12H14O5
• Molecular Weight: 238.24
• Mol File: 78423-49-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2,4,6-trihydroxy-3-(3-methyl-1-oxobutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2,4,6-trihydroxy-3-(3-methyl-1-oxobutyl)-(78423-49-1)
• EPA Substance Registry System: Benzaldehyde, 2,4,6-trihydroxy-3-(3-methyl-1-oxobutyl)-(78423-49-1)

Safety Data

• Hazardous Substances Data: 78423-49-1(Hazardous Substances Data)

Upstream product

• 26103-97-9 phloroisovalerophenone 
• 108-73-6 3,5-dihydroxyphenol 
• 108-12-3 isopentanoyl chloride 
• 68-12-2 N,N-dimethyl-formamide 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 1224583-58-7 1-[3-formyl-5-[(5-formyl-3-isopentanoyl-2,4,6-trihydroxyphenyl)-pyridin-2-yl-methyl]-2,4,6-trihydroxyphenyl]-3-methylbutan-1-one 
• 700841-14-1 methylene-bis-(3-formyl-5-isopentanoyl-2,4,6-trihydroxybenzene) 
• 1224583-59-8 1-[3-formyl-5-[(5-formyl-3-isopentanoyl-2,4,6-trihydroxyphenyl)-4-benzyloxyphenyl-methyl]-2,4,6-trihydroxyphenyl]-3-methylbutan-1-one 
• 1367716-17-3 flouren-2-yl-methylene-bis(3-isopentanoyl-5-formyl-2,4,6-trihydroxybenzene) 
• 1367716-22-0 benzofuran-2-yl-methylene-bis(3-isopentanoyl-5-formyl-2,4,6-trihydroxybenzene) 
• 1367716-26-4 4-biphenyl-1-yl-methylene-bis(3-isopentanoyl-5-formyl-2,4,6-trihydroxybenzene) 
• 1367716-19-5 imidazol-2-yl-methylene-bis(3-isopentanoyl-5-formyl-2,4,6-trihydroxybenzene) 
• 1367716-25-3 C₃₃H₃₀F₆O₁₀ 
• 1367716-24-2 C₃₂H₃₂O₁₂ 
• 1367716-15-1 pyridin-3-yl-methylene-bis(3-isopentanoyl-5-formyl-2,4,6-trihydroxybenzene) 
• 1367716-16-2 pyridin-4-yl-methylene-bis(3-isopentanoyl-5-formyl-2,4,6-trihydroxybenzene) 
• 130288-57-2 euglobal G2 
• 130304-62-0 euglobal-G₁ 
• 63861-11-0 grandinol 

Relevant articles and documents

One pot synthesis and anticancer activity of dimeric phloroglucinols

A series of dimeric phloroglucinol compounds were synthesized in a single step using commercially available phloroglucinol and methanesulfonic acid. Based on the reported anticancer activity of plant derived dimeric phloroglucinols, these synthesized comp

Biomimetic synthesis, antimicrobial, antileishmanial and antimalarial activities of euglobals and their analogues

In the present communication, naturally occurring phloroglucinol- monoterpene adducts, euglobals G1-G4 (3b/a and 4a/b) and 16 new analogues (13a/b-18a/b and 19-22) were synthesized by biomimetic approach. These synthetic compounds differ from natural euglobals in the nature of monoterpene and acyl functionality. All of these compounds were evaluated for their antibacterial, antifungal, antileishmanial and antimalarial activities. Analogue 17b possessed good antibacterial activity against methicillin-resistant Staphylococcus aureus, while analogues 19-22 possessed potent antifungal activity against Candida glabrata with IC50s ranging from 1.5 to 2.5 μg/mL. Euglobals along with all synthesized analogues exhibited antileishmanial activity. Amongst these, euglobal G2 (3a), G3 (4a) and analogues 13a and 14a showed potent antileishmanial activity with IC50s ranging from 2.8 to 3.9 μg/mL. Analogue 16a possessed antimalarial activity against chloroquine sensitive D6 clone of Plasmodium falciparum. None of the compounds showed toxicity against mammalian kidney fibroblasts (vero cells) upto the concentration of 4.76 μg/ml.

Macrocarpals, Antibacterial Compounds from Eucalyptus, Inhibit Aldose Reductase

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