78461-92-4Relevant academic research and scientific papers
An enantiomeric discrimination in aqueous mixed chiral micelles through hydrogen bonding
Jursic
, p. 963 - 966 (1993)
Self-assembling molecular receptor comprising a chiral surfactant amide placed in a rigid micellar environment recognizes the different amide enantiomeric forms in water solutions by means of hydrogen bonding.
Structural modifications of the serotonin 5-HT7 receptor agonist N -(4-cyanophenylmethyl)-4-(2-biphenyl)-1-piperazinehexanamide (LP-211) to improve in vitro microsomal stability: A case study
Lacivita, Enza,Podlewska, Sabina,Speranza, Luisa,Niso, Mauro,Sata?a, Grzegorz,Perrone, Roberto,Perrone-Capano, Carla,Bojarski, Andrzej J.,Leopoldo, Marcello
supporting information, p. 363 - 379 (2016/07/06)
The 5-HT7 serotonin receptor is revealing a promising target for innovative therapeutic strategies of neurodevelopmental and neuropsychiatric disorders. Here, we report the synthesis of thirty long-chain arylpiperazine analogs of the selective
Structural requirements for adrenergic α-receptor covalent occupancy by chiral tetramine disulfides
Brasili,Giannella,Melchiorre,et al.
, p. 115 - 118 (2007/10/02)
Chiral tetramine disulfides, designed to study the molecular properties of the active site of the adrenergic α-receptor, were synthesized and tested on rat vas deferens preparation. The activity of the three optical isomers showed that the receptor displa
