78462-10-9Relevant academic research and scientific papers
Squaric Acids: A New Motif for Designing Inhibitors of Protein Tyrosine Phosphatases
Xie, Jian,Comeau, Anthony B.,Seto, Christopher T.
, p. 83 - 86 (2007/10/03)
(Equation presented) Protein tyrosine phosphatases (PTPases) are important targets in medicinal chemistry. These enzymes play a role in a number of human diseases, including type II diabetes and infection by Yersinia pestis, the causative agent of bubonic
Oxocarbons and Related Compounds; Part 15. Meerwein-Arylation of Semisquaric Acid and Semisquaric Amides. A General Method for the Preparation of 3-Aryl-4-hydroxy- and 3-Amino-4-aryl-3-cyclobutene-1,2-diones.
Schmidt, Arthur H.,Schmitt, Guenter,Diedrich, Heike
, p. 579 - 582 (2007/10/02)
Meerwein-arylation of semisquaric acid (1) and semisquaric amides 4 has been found to afford general routes to 3-aryl-4-hydroxy-3-cyclobutene-1,2-diones 3 and 3-amino-4-aryl-3-cyclobutene-1,2-diones 5 respectively.
