78464-95-6Relevant academic research and scientific papers
Anomeric activation of thioglycosides and preparation of deoxyglycosides using polymer-bound iodate(I) complexes
Jaunzems, Janis,Sourkouni-Argirusi, Georgia,Jesberger, Martin,Kirschning, Andreas
, p. 637 - 639 (2003)
New thiophilic polymer-bound haloate(I) complexes are presented which are well suited for the polymer-assisted solution-phase activation of 2-deoxythioglycosides. In the presence of alcohols 2-deoxyglycosides are obtained in yields between 60 and 95%. Isolation of the target glycosides is further simplified by removing the byproduct diphenyldisulfide by reductive work-up. Here also a polymer-bound reagent, namely borohydride exchange resin, served as a tool for sequestering the sulfur-containing impurities.
