78467-89-7

Upstream product

• 22293-47-6 3-(α-methylphenethyl)sydnone imine 
• 30825-14-0 (1-methyl-2-phenylethylamino)acetonitrile 
• 3441-64-3 3-(α-methylphenethyl)sydnone imine hydrochloride 

Downstream Products

• 117015-66-4 N₆-(Mesitylcarbamoyl)-3-phenylisopropylsydnone imine 
• 117015-67-5 N₆-(4-Methyl-3-chlorophenylcarbamoyl)-3-phenylisopropylsydnone imine 
• 78915-45-4 N₆-Ethoxycarbonylbenzyl-3-phenylisopropylsydnonimine 
• 117038-04-7 N₆-<4-(2-Diethylaminoethoxycarbonyl)phenylcarbamoyl>-3-phenylisopropylsydnone imine 
• 3441-64-3 3-(α-methylphenethyl)sydnone imine hydrochloride 
• 87514-44-1 N⁶-(4-methyl-1,3,2-dioxaphosphorinan-2-yl)-3-(α-methylphenethyl)sydnone imine 
• 117015-64-2 N₆-(2-Tolyl-carbamoyl)-3-phenylisopropylsydnone imine 

Relevant academic research and scientific papers

Synthesis and characterization of hydroxylated mesocarb metabolites for doping control

The synthesis and method of analysis of hydroxylated mesocarb metabolites are described. Six potential hydroxylated mesocarb metabolites were prepared, characterized, and compared with the mesocarb metabolites synthesized enzymatically in vitro using human liver proteins and also compared with metabolites extracted from human urine after oral administration of mesocarb. p-Hydroxymesocarb was the most prevalent metabolite (conjugated and non-conjugated) observed. With respect to doping analysis, synthesis of p-hydroxymesocarb, the main urinary metabolite of mesocarb, and its availability as a reference material is important.

A SYDNONEIMINE BASE

It was shown by means of the UV spectra that a sydnoneimine base is formed from 3-cyclohexyl sydnoneimine hydrochloride by the action of an equivalent amount of sodium hydroxide in solutions of absolute alcohols.The sydnoneimine base is also formed in the case of solvolysis of N6-trimethylsilyl-3-cyclohexylsydnoneimine in methanol.The sydnoneimine base in solutions exists in equilibrium with the chain isomer, viz., the nitrile.The fraction of the cyclic isomer increases as the electron-donor properties of the substituent in the 3 position become more pronounced.