78482-12-9

Upstream product

• 25354-83-0 (Z)-ethyl 2-benzoyl-3-(4'-chlorophenyl)-3-propenoate 
• 100784-59-6 4-(p-chlorophenyl)-3-cyano-5-ethoxycarbonyl-6-hydroxy-6-phenylpiperidin-2-one 
• 75617-42-4 6-amino-4-(4-chloro-phenyl)-5-cyano-2-phenyl-4H-pyran-3-carboxylic acid ethyl ester 

Downstream Products

• 100784-60-9 ethyl 4-(4-chlorophenyl)-5-cyano-1,6-dihydro-6-oxo-2-phenyl-3-pyridinecarboxylate 

Relevant academic research and scientific papers

Synhesis of Heterocyclic Compounds. Part 46. The reactions of Malonamide and 2-Cyanoacetamide with Substituted Propenones

The synthesis of substituted 2-pyridone derivatives from malonamide (1) and 2-cyanoacetamide (2) is reported.Conjugate addition of these compounds to substituted propenones (3) and (4) leads to 6-hydroxy-2-piperidones, which can be dehydrated and aromatiz

Ring Transformations of 4H-Pyrans. Pyridines from 2-Amino-4H-Pyrans

Ring transformations of 4H-pyrans into pyridines are reported.Treatment of 2-amino-4,6-diaryl-3,5-dicyano-4H-pyrans (I) with nitrosylsulfuric acid brings about their transformation into 3,5-dicyano-4,6-diaryl-2-pyridones (VI) which can also be obtained fr