78482-15-2Relevant academic research and scientific papers
Ring Transformations of 4H-Pyrans. Pyridines from 2-Amino-4H-Pyrans
Seoane, Carlos,Soto, Jose L.,Zamorano, Pilar,Quinteiro, Margarita
, p. 309 - 314 (2007/10/02)
Ring transformations of 4H-pyrans into pyridines are reported.Treatment of 2-amino-4,6-diaryl-3,5-dicyano-4H-pyrans (I) with nitrosylsulfuric acid brings about their transformation into 3,5-dicyano-4,6-diaryl-2-pyridones (VI) which can also be obtained fr
SYNTHESIS OF HETEROCYCLIC COMPOUNDS XIX PREPARATION OF 4,6-DIARYL-3,5-DICYANO-2-PYRIDONES
Seoane, C.,Soto, J. L.,Zamorano, M. P.
, p. 639 - 642 (2007/10/02)
Reaction of cyanoacetamide with α-benzoylcinnamonitriles (I) leads to a new series of 4,6-diaryl-3,5-dicyano-2-pyridones (IV). The initial Michael's addition is followed by a cyclization to a 6-hydroxy-2-piperidone ring (II), whose acid dehydration gives rise to 3,4-dihydro-2-pyridones (III).The latter are easily aromatized to 4,6-diaryl-3,5-dicyano-2-pyridones (IV) by treatment with sodium nitrite in sulfuric acid.
