78482-50-5

Upstream product

• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 6134-57-2 pentane-2,3,4-trione 3-phenylhydrazone 
• 56276-49-4 3-phenylazo-pentane-2,4-dione 

Downstream Products

• 1228532-42-0 1-phenyl-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one 
• 78482-51-6 1-phenyl-3-(1H-pyrazol-3-yl)-4-(1H)pyridazinone 

Relevant academic research and scientific papers

Pyridazinone compounds

The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound of formula (I0): wherein R1 represents a substituent, R2 represents a hydrogen atom, or a substituent, R3 represents a hydrogen atom, or a substituent, Ring A represents an aromatic ring which can be substituted, and Ring B represents a 5-membered heteroaromatic ring which can be substituted, or a salt thereof.

Studies on the Synthesis of Heterocyclic Compounds. Part V. A Novel Synthesis of Some Pyridazin-4-(1H)one Derivatives and their Reaction with Hydrazine

Some phenylazo derivatives of β-dicarbonyl compounds 1a,b,c,d reacted with dimethylformamide dimethylacetal to yield new 1-phenyl-3-R-4-(1H)pyridazinones 3a,e and 4.When compounds 3a and 3e were treated with hydrazine hydrate, they gave rise to pyrazolo4