78501-31-2Relevant academic research and scientific papers
Synthesis of multisubstituted furans via Cu(i)-catalyzed annulation of ketones with alkynoate under ligand- and additive-free conditions
Luo, Zaigang,Fang, Yuyu,Zhao, Yu,Liu, Peng,Xu, Xuemei,Feng, Chengtao,Li, Zhong,He, Jie
, p. 5436 - 5441 (2016/02/05)
A facile and efficient annulation strategy for the synthesis of multisubstituted furan derivatives has been achieved under mild conditions. The developed transformation via C(sp3)-H bond functionalization catalyzed by copper(i) salts using benz
Base-catalysed Rearrangements involvung Ylide Intermediates. Part 8. The Preparation and Some Reactions of Stable Ammonium Ylides
Jemison, Robert W.,Mageswaran, Sivapathasuntharam,Ollis, W. David,Sutherland, Ian O.,Thebtaranonth, Yodhathai
, p. 1154 - 1164 (2007/10/02)
The carbonyl-stabilised ammonium ylides (3), (12a-n), and (14a-c) were obtained from the reaction of the corresponding ammonium halides (1), (13a-n), and (15a-c) with sodium hydroxide in water or aqueous methanol.The ylides, which were characterised by their molecular formulae and spectroscopic properies, regenerated quaternary ammonium bromides on treatment with hydrobromic acid.In general the reactions of the ammonium ylides resemble those of the corresponding sulphonium ylides.Thus ylides having a suitable migrating group (ArCH2) undergo a Stevens rearrangement on heating, and other ylides fragment to give a tertiary amine and products containing the PhCOCH grouping.A number of ylides reacted with dimethyl acetylenedicarboxylate to give the furans (32).The ylides (14b and c) with phenyl isocyanate gave the phenylcarbamoyl-substituted ylides.
