78558-43-7Relevant academic research and scientific papers
6-Aryl-pyrazolo[3,4-b]pyridines: Potent inhibitors of glycogen synthase kinase-3 (GSK-3)
Witherington, Jason,Bordas, Vincent,Gaiba, Alessandra,Garton, Neil S.,Naylor, Antoinette,Rawlings, Anthony D.,Slingsby, Brian P.,Smith, David G.,Takle, Andrew K.,Ward, Robert W.
, p. 3055 - 3057 (2007/10/03)
A novel series of 6-aryl-pyrazolo[3,4-b]pyridines has been identified that are potent inhibitors of glycogen synthase kinase-3 (GSK-3).
Cephalosporin compounds
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, (2008/06/13)
Cephalosporin compounds, intermediate compounds therefor, and processes for preparation thereof are described; the compounds have the formula (I) STR1 wherein R1 and R2 can each represent hydrogen, a hydroxyl group, a lower alkoxy group, or a substituted or unsubstituted phenylalkoxy group; R3 represents hydrogen or a lower alkyl group; R4 represents hydrogen or a hydroxyl group; and R5 represents STR2 wherein R6 is hydrogen, a lower alkyl group, an aminoalkyl group, an aminoaralkyl group, a --(CH2)n --SO3 Na group, or a --(CH2)n --COR9 group [wherein R9 is a hydroxyl group, an OM group (wherein M is an alkali metal), an alkoxy group, or an STR3 group, (wherein R10 and R11, which may be the same or different, can represent hydrogen or an alkyl group), and n is 0 or an integer of from 1 to 4]; R7 is hydrogen, a lower alkyl group, an amino group, or a substituted or unsubstituted aryl group; and R8 represents hydrogen or a lower alkyl group; or, a pharmaceutically acceptable salt thereof.
Penicillin compounds
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, (2008/06/13)
Penicillin compounds and methods for the production thereof are described, said penicillin compounds being represented by the formula (I) STR1 wherein R1, R2, and R3 each represents hydrogen, a lower alkyl group, a halogen atom, a lower alkoxy group, a hydroxyl group, or a substituted or unsubstituted phenylalkoxy group except that R1, R2, and R3 cannot all represent hydrogen simultaneously; R4 represents hydrogen or a lower alkyl group; and R5 represents hydrogen or a hydroxyl group.
