785778-74-7Relevant academic research and scientific papers
A spirocyclic chiral borate for catalytic enantioselective Nozaki-Hiyama allylation of ketones
Huang, Xin-Ren,Chen, Chinpiao,Lee, Gene-Hsian,Peng, Shie-Ming
, p. 3089 - 3095 (2009)
A new class of chiral spirocyclic borate ligands 5a-d with a rigid borocycle has been developed. The catalyst formed from chromium(II)-5a promotes the highly efficient enantioselective Nozaki-Hiyama allylation of alkyl and aryl ketones using allyl bromide
Synthesis and Application of Substituted 1,16-Dihydroxytetraphenylenes in Catalytic Asymmetric Allylboration of Ketones
Chai, Guo-Li,Zhu, Bo,Chang, Junbiao
, p. 120 - 127 (2019/01/08)
The synthesis and application of a newly designed C2-symmetric chiral-substituted 1,16-dihedroxytetraphenylene (DHTP) is reported. Efficient syntheses of enantiopure substituted DHTP were accomplished, and these enantiopure compounds were used as organocatalysts in asymmetric allylboration of ketones under very mild conditions. Accordingly, several tertiary alcohols were generated in moderate to good yields with up to 99% ee by using the catalyst (S)-2,15-Br2-DHTP. A gram-scale reaction was achieved in 99% yield with 96% ee.
A chiral bipyridyl alcohol for catalytic enantioselective Nozaki-Hiyama-Kishi allylation of aldehydes and ketones
Chen, Rui-Yu,Dhondge, Attrimuni P.,Lee, Gene-Hsian,Chen, Chinpiao
supporting information, p. 961 - 966 (2015/03/30)
A class of bipyridyl alcohol ligands has been developed. A catalyst synthesized using a chromium(II)-ligand promotes the enantioselective Nozaki-Hiyama-Kishi (NHK) allylation of aldehydes and ketones with allylic halides. The allylation of various aromati
Asymmetric allylation of ketones and subsequent tandem reactions catalyzed by a novel polymer-supported titanium-binolate complex
Yadav, Jagjit,Stanton, Gretchen R.,Fan, Xinyuan,Robinson, Jerome R.,Schelter, Eric J.,Walsh, Patrick J.,Pericas, Miquel A.
supporting information, p. 7122 - 7127 (2014/06/09)
By using a novel, simple, and convenient synthetic route, enantiopure 6-ethynyl-BINOL (BINOL=1,1-binaphthol) was synthesized and anchored to an azidomethylpolystyrene resin through a copper-catalyzed alkyne-azide cycloaddition (CuAAC) reaction. The polyst
