785817-89-2Relevant academic research and scientific papers
Kinetic resolution of d,l-myo-inositol derivatives catalyzed by chiral Cu(II) complex
Matsumura, Yoshihiro,Maki, Toshihide,Tsurumaki, Kazuya,Onomura, Osamu
, p. 9131 - 9134 (2004)
Kinetic resolution of d,l-myo-inositol derivatives having a 1,2-diol functionality by monobenzoylation was achieved using (R,R)-Ph-BOX-Cu(II) as a catalyst. The monobenzoylation preferentially took place at the 1,2-diol functionality via a highly enantiod
Desymmetrization of 4,6-diprotected myo-inositol
Lauber, Markus B.,Daniliuc, Constantin-Gabriel,Paradies, Jan
supporting information, p. 7409 - 7411 (2013/09/23)
The asymmetric desymmetrization of 4,6-diprotected myo-inositol derivatives was achieved by using a bifunctional, readily available nucleophilic catalyst. The orthogonally protected products were obtained in 80-99% yield with 90-99% ee. Such structures serve as potential enantiopure building blocks for the synthesis of myo-inositol phosphates.
